Protein Alignment tkv and daf-1

DIOPT Version :9

• Sequence 1: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001023159.1
• Gene: daf-1 / 176829
• WormBaseID: WBGene00000897
• Length: 669
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 182/632 - (28%)
• Similarity: 275/632 - (43%)
• Gaps: 138/632 - (21%)

  Fly    18 DGLFEEIALEALTRSEFS----ANVQPDVEAMAAAALSGMEMGSGPGSEGYEDADNEKSKTVENA 78
            |.|...:.|..:|:..|:    .:...:|...|...      |..||.|...:.|.   ...||
 Worm    34 DKLIPALKLAEVTKVNFTRLHLCHCSREVGCNARTT------GWVPGIEFLNETDR---SFYEN- 88

  Fly    79 RSLTCYCDGSCPDNVSNGTCETRPGGSCFSAVQQLYDETTGMYEEERTYGCMPPE---DNGGF-- 138
               |||.||||..:       .||.                  .|...:|||..:   |...|
 Worm    89 ---TCYTDGSCYQS-------ARPS------------------PEISHFGCMDEKSVTDETEFHD 125

  Fly   139 LMCKVAA--VPHLHGKNIVCCDKEDFCNRDLYPTYTPKLTTPAPDLPVSSESLHTLAVFGSIIIS 201
            ...||..  ....|....:||||.:||..:......|.        |..|.:...|    :|:..
 Worm   126 TAAKVCTNNTKDPHATVWICCDKGNFCANETIIHLAPG--------PQQSSTWLIL----TILAL 178

  Fly   202 LSVFMLIVASLCFTYKRREK-----LRKQPR---------------------------------- 227
            |:..:|:..::..|.|..|.     :|.:|:
 Worm   179 LTFIVLLGIAIFLTRKSWEAKFDWYIRFKPKPGDPLRETENNVPMVTMGDGAGSSVPEVAPIEQQ 243

  Fly   228 ---LINSMCNS--------QLSPLSQLVEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVW 281
               :..|..||        .:..:..::|::||||.|...|.:.||..||::...||.||:|.|.
 Worm   244 GSTMSTSAGNSFPPGIMPNNMKDMLDVLEETSGSGMGPTTLHKLTIGGQIRLTGRVGSGRFGNVS 308

  Fly   282 LAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEM 346
            ...:|.|.||||.|...:|.::.:||||::|.::||.|:|.:|.:|....|..|::.|:|:||..
 Worm   309 RGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPS 373

  Fly   347 GSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGT--PGKPAIAHRDIKSKNILVKRNGQCA 409
            |||||:|..:.:|.:....|..|.|||||.||::|.|:  ..|||:||||||||||:||.:..||
 Worm   374 GSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCA 438

  Fly   410 IADFGLAVK--YNSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMYSVGLVLWEM 472
            |.|.||::.  .::..|:| ..:|.:.||.||:|||:|:..:....||.::.||:||..||:||.
 Worm   439 IGDLGLSLSKPEDAASDII-ANENYKCGTVRYLAPEILNSTMQFTVFESYQCADVYSFSLVMWET 502

  Fly   473 TRRCYTPVSGTKTTTCED---------YALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQED 528
            ..|            |||         ..:||.:....||....|..|||.:..||.....|::.
 Worm   503 LCR------------CEDGDVLPREAATVIPYIEWTDRDPQDAQMFDVVCTRRLRPTENPLWKDH 555

  Fly   529 DVLATVSKIMQECWHPNPTVRLTALRVKKTLGRLETDCLIDVPIKIV 575
            ..:..:.:|::.||:.||:.|.|:...:|.:...: ..|:|...|.|
 Worm   556 PEMKHIMEIIKTCWNGNPSARFTSYICRKRMDERQ-QLLLDKKAKAV 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tkv	NP_787990.1	Activin_recp	81..171	CDD:279413	24/96 (25%)
		GS	238..266	CDD:197743	9/27 (33%)
		S_TKc	267..557	CDD:214567	113/302 (37%)
		STKc_BMPR1	270..562	CDD:271046	114/304 (38%)
daf-1	NP_001023159.1	GS	265..293	CDD:197743	9/27 (33%)
		Pkinase_Tyr	293..576	CDD:285015	112/295 (38%)
		STKc_TGFbR_I	297..589	CDD:270958	114/304 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	1	1.000	-	-		otm14704
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910