Protein Alignment tkv and bmpr2

DIOPT Version :10

• Sequence 1: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_002937761.3
• Gene: bmpr2 / 100494339
• XenbaseID: XB-GENE-479990
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 160/543 - (29%)
• Similarity: 250/543 - (46%)
• Gaps: 90/543 - (16%)

  Fly    55 MGSGPGSE------GYEDADNEKSKTVENARSLTCYCDGSCPDNVSNGTCETRPGGSCFSAVQQL 113
            :.:.|.::      .|:|.:|:.....|:..||            .|||.:...|..||...::.
 Frog    40 LATAPATQSEERLCAYKDPNNQDQALSESQISL------------ENGTVKCTKGNICFGLWEKT 92

  Fly   114 YD---------------ETTGMYEEERTYGCMPPE-DNGGFLMCKVAAVPHLHGKNIVCCDKEDF 162
            .|               ::...|.||......||. .||.:..|              ||.| |.
 Frog    93 RDGEINLVRQGCWSHVSDSRDCYYEECAVTTPPPVIQNGTYRFC--------------CCSK-DM 142

  Fly   163 CNRDLYPTYTPKLTTPAPDLPVS-SESLHTLAVFGSIIISLSVFMLIVASLCFTYKRREKLRKQP 226
            ||.:....:||  :.|....|.| |..||........:.|:||..:::....|.|:.....|||.
 Frog   143 CNVNFTENFTP--SDPTSASPYSPSGWLHREMTIIIALASISVLAVLIVVFFFGYRIFGGDRKQG 205

  Fly   227 RLINSMCNSQLSPLSQLVEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVA 291
              ::||          .|.:::.|...|.|       ..::::.|:|:||||.|:.....:..||
 Frog   206 --LHSM----------NVLEAATSEPSLDL-------DNLKLLELIGRGRYGSVYKGSLDERPVA 251

  Fly   292 VKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAAD--IKGNGSWTQMLLITDYHEMGSLHDYLS 354
            ||.|......::..|..||:|.|:.||||..|||||  |..:|. .:.||:.:|:..|||..|||
 Frog   252 VKVFSFNNRQNFINERSIYRTPLLEHDNIAHFIAADERITSDGR-LEYLLVMEYYANGSLSKYLS 315

  Fly   355 MSVINPQKLQLLAFSLASGLAHLHDEIF-GTPGKPAIAHRDIKSKNILVKRNGQCAIADFGLAVK 418
            :...:......||.|:..|||:||.|:. |...|.||:|||:.|:|:|||.:|.|.|:||||:::
 Frog   316 VHSNDWLNSCRLAHSVTKGLAYLHTELLRGDNYKSAISHRDLNSRNVLVKSDGTCVISDFGLSMR 380

  Fly   419 YN-------SELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEE-FKRADMYSVGLVLWEMTRR 475
            ..       .:.|...|::   |||.||||||||...::.:..|. .|:.|||::||:.||:..|
 Frog   381 LTGNRLVRPGDEDNAAISE---VGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMR 442

  Fly   476 CYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDV-LATVSKIMQ 539
            |.....|   .:..:|.:.:.....:.||||||..:|..:..||..|..|:|:.: :.::.:.:.
 Frog   443 CTDLFPG---ESVPEYQMAFQTEAGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETID 504

  Fly   540 ECWHPNPTVRLTALRVKKTLGRL 562
            :||..:...||||...::.:..|
 Frog   505 DCWDQDAEARLTAQCAEERMAEL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tkv	NP_787990.1	TFP_LU_ECD_Tkv	81..169	CDD:467125	22/103 (21%)
		GS	238..266	CDD:197743	4/27 (15%)
		STKc_BMPR1	270..562	CDD:271046	109/303 (36%)
bmpr2	XP_002937761.3	TFP_LU_ECD_BMPR2	51..151	CDD:467134	27/126 (21%)
		STKc_BMPR2_AMHR2	230..527	CDD:270956	109/303 (36%)