Protein Alignment tkv and acvr2ab

DIOPT Version :9

• Sequence 1: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_009300361.1
• Gene: acvr2ab / 100331014
• ZFINID: ZDB-GENE-120215-23
• Length: 439
• Species: Danio rerio
• Alignment Length: 437
• Identity: 159/437 - (36%)
• Similarity: 225/437 - (51%)
• Gaps: 63/437 - (14%)

  Fly   156 CCDKEDFCNRDLY-------PTYTPKLTTPAPDLPVSSESLHTLAVFGSIIISLSVFM--LIVAS 211
            ||.:.:.||:..:       ||..|  ..|.|||            |.:::.||...|  .::..
Zfish    31 CCCEGNLCNQKFHYNPETVEPTLNP--VPPKPDL------------FPTLLYSLLPIMAVAVILF 81

  Fly   212 LCFTYKRREKLRKQPRLINSMCNSQLSPLSQLVEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGR 276
            :.|...|..||...|.|:.|. :..|:|.|             |||.|    |.:|::.|..:||
Zfish    82 ISFWMYRHLKLTYPPLLVPSQ-DPGLTPPS-------------PLLGQ----KPLQLLELKARGR 128

  Fly   277 YGEVWLAKWRDERVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWTQMLLIT 341
            :|.||.|:...|.||||.|....:.||..|.|||....|:|:|:|.||.|:.:|||...::.|||
Zfish   129 FGCVWKAQLLSEAVAVKIFPVQNKQSWQNEYEIYNASGMKHENLLHFIGAEKRGNGVDIELWLIT 193

  Fly   342 DYHEMGSLHDYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTPG-----KPAIAHRDIKSKNIL 401
            .|||.|||.|:|..:|::..:|.|:|.:...|||:||::|   |.     |||||||||||||:|
Zfish   194 TYHEKGSLTDFLKANVLSWNELCLIAQTFVRGLAYLHEDI---PNLKDGHKPAIAHRDIKSKNVL 255

  Fly   402 VKRNGQCAIADFGLAVKY---NSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMY 463
            :|.:....|||||||:|:   .|..|.     :.:||||||||||||...:. .|.:.|.|.|||
Zfish   256 LKSDLTACIADFGLALKFEAGKSTGDT-----HGQVGTRRYMAPEVLEGAIS-FQRDAFLRIDMY 314

  Fly   464 SVGLVLWEMTRRCYTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQED 528
            :.||||||:..|| |...|    ..:::.||:.:.....|:.|||..||..|..||.....|.:.
Zfish   315 AAGLVLWELATRC-TAADG----PVDEFCLPFEEEAGLHPSLEDMQDVVVHKKLRPIFREHWLKH 374

  Fly   529 DVLATVSKIMQECWHPNPTVRLTALRVKKTLGRLETDCLIDVPIKIV 575
            ..|:.:.:.|:|||......||:|..|::.:..::....|..|..|:
Zfish   375 TGLSLLCETMEECWDHEAEARLSAGCVEERIISMQRSTSIISPDDIL 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tkv	NP_787990.1	Activin_recp	81..171	CDD:279413	5/21 (24%)
		GS	238..266	CDD:197743	7/27 (26%)
		S_TKc	267..557	CDD:214567	126/297 (42%)
		STKc_BMPR1	270..562	CDD:271046	125/299 (42%)
acvr2ab	XP_009300361.1	Activin_recp	<1..46	CDD:279413	4/14 (29%)
		STKc_ACVR2	122..411	CDD:270955	125/302 (41%)
		S_TKc	126..398	CDD:214567	122/285 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840