Protein Alignment tkv and acvr2ab

DIOPT Version :10

• Sequence 1: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_073809589.1
• Gene: acvr2ab / 100331014
• ZFINID: ZDB-GENE-120215-23
• Length: 511
• Species: Danio rerio
• Alignment Length: 535
• Identity: 176/535 - (32%)
• Similarity: 251/535 - (46%)
• Gaps: 99/535 - (18%)

  Fly    58 GPGSEGYEDADNEKSKTVENARSLTCYCDGSCPDNVSNGTCETRPGGSCFSAVQQLYDETTGMYE 122
            |....|.|....||.|        ..:|..:..:.  :||.|....| |:......||.:.
Zfish    41 GTNRSGTESCYGEKDK--------RRHCFSTWKNR--SGTIEMVKQG-CWLDDVNCYDSSE---- 90

  Fly   123 EERTYGCMPPEDNGGFLMCKVAAVPHLHGKNIVCCDKEDFCNRDLY-------PTYTPKLTTPAP 180
                  |:..::|.....|              ||: .:.||:..:       ||..|  ..|.|
Zfish    91 ------CVERKENIDVFFC--------------CCE-GNLCNQKFHYNPETVEPTLNP--VPPKP 132

  Fly   181 DLPVSSESLHTLAVFGSIIISLSVFM--LIVASLCFTYKRREKLRKQPRLINSMCNSQLSPLSQL 243
            ||            |.:::.||...|  .::..:.|...|..||...|.|:.|. :..|:|.|
Zfish   133 DL------------FPTLLYSLLPIMAVAVILFISFWMYRHLKLTYPPLLVPSQ-DPGLTPPS-- 182

  Fly   244 VEQSSGSGSGLPLLVQRTIAKQIQMVRLVGKGRYGEVWLAKWRDERVAVKTFFTTEEASWFRETE 308
                       |||.|    |.:|::.|..:||:|.||.|:...|.||||.|....:.||..|.|
Zfish   183 -----------PLLGQ----KPLQLLELKARGRFGCVWKAQLLSEAVAVKIFPVQNKQSWQNEYE 232

  Fly   309 IYQTVLMRHDNILGFIAADIKGNGSWTQMLLITDYHEMGSLHDYLSMSVINPQKLQLLAFSLASG 373
            ||....|:|:|:|.||.|:.:|||...::.|||.|||.|||.|:|..:|::..:|.|:|.:...|
Zfish   233 IYNASGMKHENLLHFIGAEKRGNGVDIELWLITTYHEKGSLTDFLKANVLSWNELCLIAQTFVRG 297

  Fly   374 LAHLHDEIFGTPG-----KPAIAHRDIKSKNILVKRNGQCAIADFGLAVKY---NSELDVIHIAQ 430
            ||:||::|   |.     |||||||||||||:|:|.:....|||||||:|:   .|..|.
Zfish   298 LAYLHEDI---PNLKDGHKPAIAHRDIKSKNVLLKSDLTACIADFGLALKFEAGKSTGDT----- 354

  Fly   431 NPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMYSVGLVLWEMTRRCYTPVSGTKTTTCEDYALPY 495
            :.:||||||||||||...:. .|.:.|.|.|||:.||||||:..|| |...|    ..:::.||:
Zfish   355 HGQVGTRRYMAPEVLEGAIS-FQRDAFLRIDMYAAGLVLWELATRC-TAADG----PVDEFCLPF 413

  Fly   496 HDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATVSKIMQECWHPNPTVRLTALRVKKTLG 560
            .:.....|:.|||..||..|..||.....|.:...|:.:.:.|:|||......||:|..|::.:.
Zfish   414 EEEAGLHPSLEDMQDVVVHKKLRPIFREHWLKHTGLSLLCETMEECWDHEAEARLSAGCVEERII 478

  Fly   561 RLETDCLIDVPIKIV 575
            .::....|..|..|:
Zfish   479 SMQRSTSIISPDDIL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tkv	NP_787990.1	TFP_LU_ECD_Tkv	81..169	CDD:467125	15/94 (16%)
		GS	238..266	CDD:197743	7/27 (26%)
		STKc_BMPR1	270..562	CDD:271046	125/299 (42%)
acvr2ab	XP_073809589.1	None