Protein Alignment CG14034 and PNLIP

DIOPT Version :9

• Sequence 1: NP_001036339.1
• Gene: CG14034 / 33751
• FlyBaseID: FBgn0250847
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 111/387 - (28%)
• Similarity: 168/387 - (43%)
• Gaps: 78/387 - (20%)

  Fly    13 SVML--VAG----LDDMNCFSLQN----------EICP----NANISFWLYTKENQEGTKLSVFE 57
            |::|  |||    .:.:.|||..:          .|.|    :.|..|.|||.||.
Human     8 SLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENP--------- 63

  Fly    58 LNRFE-------------FYHHKPLKVLIHGF--NGHRDFSPNTQLRPLFLTQDYNLISLDYPKL 107
             |.|:             |..::..:.:||||  .|..::..|. .:.||..:..|.|.:|: |.
Human    64 -NNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANV-CKNLFKVESVNCICVDW-KG 125

  Fly   108 AYEPCYTEAVHNAKYVARCTAQLLRVLLESGLVKIEDLHLIGLGLGAHVAGFIGQFLPEHKLEHI 172
            .....||:|..|.:.|....|..:..|..:......::|:||..||||.||..|: .....:..|
Human   126 GSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGR-RTNGTIGRI 189

  Fly   173 TALDPAKPFYMVKDPALKLDPTDAKFVDVVHTDVTML------GLLDAVGHVDFYLNMGVSQPNC 231
            |.||||:|.:......::|||:|||||||:|||...:      |:...|||:||:.|.||..|.|
Human   190 TGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEMPGC 254

  Fly   232 --GPINKM-----------ETHFCYHNRAADYYAESISSPSGFYGFYCPNFKSFAKGICI--PDK 281
              ..::::           :...|.|.|:..||.:||.:|.||.||.|.::..|....|.  |..
Human   255 KKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCPSG 319

  Fly   282 NIELMGFHVD--PKARG----RYFLDTNNGPPYAKGENFTSISRQLKGRTFVNDDIIDKLIG 337
            ....||.:.|  |....    :::|||.:...:|:.....|::  |.|:. |...|:..|.|
Human   320 GCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVT--LSGKK-VTGHILVSLFG 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14034	NP_001036339.1	Pancreat_lipase_like	37..303	CDD:238363	92/307 (30%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:278576	98/347 (28%)
		PLAT_PL	355..465	CDD:238857	7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940