DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14034 and pla1a

DIOPT Version :9

Sequence 1:	NP_001036339.1	Gene:	CG14034 / 33751	FlyBaseID:	FBgn0250847	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_996939.1	Gene:	pla1a / 334017	ZFINID:	ZDB-GENE-030131-5949	Length:	456	Species:	Danio rerio

Alignment Length:	340	Identity:	104/340 - (30%)
Similarity:	148/340 - (43%)	Gaps:	55/340 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FSSVMLVAGLDDMNCFSLQNEICPNANISFWLYTKENQEGTKL---------------SVFE--- 57
            :.||.:.:.|.|....|...  |.:.|.:.||   |.::.|||               |:|.
Zfish    11 YLSVCVTSALGDDEEASASK--CADFNNTTWL---EYRQATKLQVQYLLLTRKNANCASLFTQDC 70

  Fly    58 LNRFE-----FYHHKPLKVLIHGFN--GHRDFSPNTQLRPLFLTQDYNLISLDYPKLAYEP--CY 113
            ||..:     |....|.||::||:.  |.:....:...:.|...:|.|::.:|:   .|..  .|
Zfish    71 LNHTQKHTAYFNSSLPTKVIVHGYRALGSKPSWVSGLAQALLREEDVNVLVVDW---VYGASFAY 132

  Fly   114 TEAVHNAKYVARCTAQLLRVLLESGLVKIEDLHLIGLGLGAHVAGFIGQFLPEHKLEHITALDPA 178
            ...|.|.|.||...:.|:..|.:.|.. :|..|.||:.|||||:||:|. |...||..||.||||
Zfish   133 NLVVENYKEVAVQISVLINQLTKYGST-LESFHFIGVSLGAHVSGFVGT-LFHGKLGRITGLDPA 195

  Fly   179 KPFYMVKDPALKLDPTDAKFVDVVHTDVTMLGLLDAVGHVDFYLNMGVSQPNCGPINKMETH--- 240
            .|.:...||..:||.:||.||:.:|||....|:...||||||:||.|:.|..|........:
Zfish   196 GPMFKSADPFDRLDSSDALFVEAIHTDSDYFGISIPVGHVDFFLNGGMDQAGCARSRFASMYGYV 260

  Fly   241 FCYHNRAADYYAESISSPSGFYGFYCPNFKSFAKGICI----------PD----KNIELMGFHVD 291
            .|.|.||...|..:::......||.|..::.|..|.||          |.    ||..:....:
Zfish   261 ICDHMRALHVYMSALNGSCPLIGFPCSGYEEFLAGKCITCDDPFNGTCPQIGLLKNSGITATPL- 324

  Fly   292 PKARGRYFLDTNNGP 306
            |.....|.|.|.:||
Zfish   325 PNQEKVYLLTTASGP 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14034	NP_001036339.1	Pancreat_lipase_like	37..303	CDD:238363	95/309 (31%)
pla1a	NP_996939.1	Lipase	21..340	CDD:278576	101/330 (31%)
pla1a	NP_996939.1	Pancreat_lipase_like	48..336	CDD:238363	89/293 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010