Protein Alignment IAPP and Iapp

DIOPT Version :10

• Sequence 1: NP_000406.1
• Gene: IAPP / 3375
• HGNCID: 5329
• Length: 89
• Species: Homo sapiens
• Sequence 2: NP_036718.1
• Gene: Iapp / 24476
• RGDID: 2854
• Length: 93
• Species: Rattus norvegicus
• Alignment Length: 90
• Identity: 59/90 - (65%)
• Similarity: 68/90 - (75%)
• Gaps: 3/90 - (3%)

Human     3 ILKLQVFLIVLSVALNHLKATPIES---HQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTN 64
            |.:|...|::|||||.||:|||:.|   .||:|||||||||||||||||||.||||.|.:|..||
  Rat     4 ISRLPAVLLILSVALGHLRATPVGSGTNPQVDKRKCNTATCATQRLANFLVRSSNNLGPVLPPTN 68

Human    65 VGSNTYGKRNAVEVLKREPLNYLPL 89
            ||||||||||..|...||.|::|.|
  Rat    69 VGSNTYGKRNVAEDPNRESLDFLLL 93

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IAPP	NP_000406.1	Calc_CGRP_IAPP	<27..73	CDD:459715	37/48 (77%)
Iapp	NP_036718.1	Calc_CGRP_IAPP	<36..77	CDD:459715	34/40 (85%)