Protein Alignment IAPP and Iapp

DIOPT Version :10

• Sequence 1: NP_000406.1
• Gene: IAPP / 3375
• HGNCID: 5329
• Length: 89
• Species: Homo sapiens
• Sequence 2: NP_034621.1
• Gene: Iapp / 15874
• MGIID: 96382
• Length: 93
• Species: Mus musculus
• Alignment Length: 90
• Identity: 60/90 - (66%)
• Similarity: 69/90 - (76%)
• Gaps: 3/90 - (3%)

Human     1 MGILKLQVFLIVLSVALNHLKATPIES---HQVEKRKCNTATCATQRLANFLVHSSNNFGAILSS 62
            |.|.||...|::||||||||:|||:.|   .|::|||||||||||||||||||.||||.|.:|..
Mouse     2 MCISKLPAVLLILSVALNHLRATPVRSGSNPQMDKRKCNTATCATQRLANFLVRSSNNLGPVLPP 66

Human    63 TNVGSNTYGKRNAVEVLKREPLNYL 87
            |||||||||||||.....||.|::|
Mouse    67 TNVGSNTYGKRNAAGDPNRESLDFL 91

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IAPP	NP_000406.1	Calc_CGRP_IAPP	<27..73	CDD:459715	36/48 (75%)
Iapp	NP_034621.1	Calc_CGRP_IAPP	<36..77	CDD:459715	34/40 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..93		18/28 (64%)