Protein Alignment Cyp28d1 and ERG11

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 519
• Identity: 108/519 - (20%)
• Similarity: 185/519 - (35%)
• Gaps: 124/519 - (23%)

  Fly    11 IAAILALIYVF-LTWNFSY-WKKRGIPTAKSW-PFVGSFPSVFTQKRNVVYDI------DEIYEQ 66
            |:.|:.:.::: :.|...| .:|...|....| |:|||         .|||.:      :|..::
Yeast    31 ISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGS---------AVVYGMKPYEFFEECQKK 86

  Fly    67 YKNTDSIV----------------GVFQTRIPQLM-------VTTPEYAHKIYVSDFRSFHDNEM 108
            |.:..|.|                .||..::..:.       :|||.:. |..:.|..:....|.
Yeast    87 YGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFG-KGVIYDCPNSRLMEQ 150

  Fly   109 AKFTDSKTDPILANNPFVLTGEAWKERRAEVTPGLSANRVKAAYPVSLRVCKKFVEYIRRQSLMA 173
            .||...           .||.||:                |:..|:   :.::..:|.|......
Yeast   151 KKFVKG-----------ALTKEAF----------------KSYVPL---IAEEVYKYFRDSKNFR 185

  Fly   174 PAQGLNAKDLCLCYTTEVISDCVLGISAQSFTDNPTPMVGMTKRV-FEQSFGFIF------YTVV 231
                ||.:      ||..|...|.......||.:.: ::|...|. .:..|.:::      :|.:
Yeast   186 ----LNER------TTGTIDVMVTQPEMTIFTASRS-LLGKEMRAKLDTDFAYLYSDLDKGFTPI 239

  Fly   232 ANLWP--PITKFYSVSLFAKDVAAFFYDLMQKCIQVRRESPAAQQRDDFLNYMLQLQEKKGLNAA 294
            ..::|  |:..:.......|.::..:..|    |:.||::...|.||...:.|.....|.|:...
Yeast   240 NFVFPNLPLEHYRKRDHAQKAISGTYMSL----IKERRKNNDIQDRDLIDSLMKNSTYKDGVKMT 300

  Fly   295 --ELTSHTMTFLTDGFETTAQVLTHTLLFLARNPKEQMKLREEI------GTAELTFEQISELPF 351
              |:.:..:..|..|..|:|......||.||..|..|.:|.||.      |..|||::.:.|:|.
Yeast   301 DQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPL 365

  Fly   352 TEACIHETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFK 416
            ....|.||||:..|:.:..:.|.:...:.|   .|..:..|..|::.....|...:|:.....|.
Yeast   366 LNQTIKETLRMHHPLHSLFRKVMKDMHVPN---TSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFN 427

  Fly   417 PERFLNINGGAKKYR-----DQGL----------FFGFGDGPRICPGMRFSLTQIKAALVEIVR 465
            ..|:  ....|..|.     |.|.          :..||.|...|.|..|:..|:...:...:|
Yeast   428 IHRW--NKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	92/452 (20%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	93/458 (20%)