DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp28d1 and CYP705A32

DIOPT Version :9

Sequence 1:	NP_608912.1	Gene:	Cyp28d1 / 33749	FlyBaseID:	FBgn0031689	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188731.1	Gene:	CYP705A32 / 821645	AraportID:	AT3G20950	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	114/523 - (21%)
Similarity:	221/523 - (42%)	Gaps:	86/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFVIAAILALIYVFLTWNFSYWKK-------RGIPTAKSWPFVGSFPSVFTQKRNVVYDIDE-IY 64
            :|::..:.:||...|     :::|       |.:|     |...|||....|..|:...:.. ::
plant    14 IFILFCLFSLICYSL-----FFRKPKDSRAGRDLP-----PSPPSFPVGSPQSNNLHLLLSALVH 68

  Fly    65 EQYKNTDSIVG------VFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILANN 123
            :.::......|      ||  .:|.::.::...|::|    |::...|..::......:.:|..:
plant    69 KSFQKISYKYGPLLHLRVF--HVPIVLASSASVAYEI----FKAQDVNVSSRGHAPAGESLLFGS 127

  Fly   124 P---FVLTGEAWK-ERRAEVTPGLSANRVKAAYPVSLRVCKKFV-----EYIRRQS--LMAPAQG 177
            .   |...|:.:| .|:...|..|....::.:..:......:|.     :.::::|  ::..|..
plant   128 SSFFFAPYGDYFKFMRKLIATKLLGPQALERSRKIRADELDRFYRNLLDKAMKKESVDIVEEAAK 192

  Fly   178 LNAKDLC------LCYTTEVISDCVLGISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWP 236
            ||...:|      .|......::.|.|:..:|        ..:||::|   .|.||.       .
plant   193 LNNNIICKMIMGRSCSEDNGEAERVRGLVIES--------TALTKQIF---LGMIFD-------K 239

  Fly   237 PITKFYSVSLFAKDVAAF--FYDLMQKCIQVRRESPAAQQR-DDFLNYMLQLQEKKGLNAAELTS 298
            |:.|. .:|||.||:.:.  |.:|::|.:....|......: :|.::.:|:....:........:
plant   240 PLKKL-GISLFQKDIKSVSRFDELLEKILVEHEERMGKHYKANDMMDLLLEAYGDENAEYKITRN 303

  Fly   299 HTMTFLTD----GFETTAQVLTHTLLFLARNPKEQMKLREEI----GTAELTFE-QISELPFTEA 354
            |..:...|    |.:|:||.:..|:..|..||....:|||||    |...|..| .:..||:.:|
plant   304 HIKSLFVDLVIAGTDTSAQTIEWTMAELINNPNILERLREEIESVVGNTRLVQETDLPNLPYLQA 368

  Fly   355 CIHETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPER 419
            .:.|.||:..|.....:...|.|||   .|..:..:  .::::.|.|:..||:.:|:|:.|||||
plant   369 VVKEGLRLHPPGAVFLRTFQERCEL---KGFYIPEK--TLLVVNVYAIMRDPKLWEDPEEFKPER 428

  Fly   420 FL--NINGGAKKYRDQGL-FFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNPKTRKDNEI 481
            |:  :.:|...:.|::.| :..|..|.|.|||...:...:..|:..:.:.||.::..:....||.
plant   429 FIASSRSGQEDEIREEVLKYMPFSTGRRGCPGSNLAYVSVGTAIGVMAQCFDWRIKGEKVNMNEA 493

  Fly   482 DDT 484
            ..|
plant   494 AGT 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	p450	35..477	CDD:278495	105/480 (22%)
CYP705A32	NP_188731.1	p450	16..514	CDD:299894	113/521 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010