Protein Alignment Cyp28d1 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 489
• Identity: 142/489 - (29%)
• Similarity: 239/489 - (48%)
• Gaps: 51/489 - (10%)

  Fly    10 VIAAILALIYVFLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQYKNTDSIV 74
            ::|.||.|:|.:.|.....:||:|||..|..||:|:..:.:  |....:|: |.||:|..|   .
Mouse    14 LLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYY--KGLWKFDM-ECYEKYGKT---W 72

  Fly    75 GVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNE--------MAKFTDSKTDPILANNPFVLTGEA 131
            |:|..::|..::|.||....:.|.:..|...|.        |:|......|            |.
Mouse    73 GLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKD------------EE 125

  Fly   132 WKERRAEVTPGLSANRVKAAYPVSLRVCKKFVEYIRRQSLMAPAQGLNAKDLCLCYTTEVISDCV 196
            ||..||.::|..::.::|..:||..:.....|:|:.:::  ...:.:..||:...|:.:||:...
Mouse   126 WKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEA--EKGKPVTMKDVLGAYSIDVITSTS 188

  Fly   197 LGISAQSFTDNPTPMVGMTKRVFEQSF--GFIFYTVVANLWPPITKFYSVSLFAKDVAAFFYDLM 259
            .|::..|..:...|.|...|.:....|  ..:|..|:.....|:.:..::.:|.||...||...:
Mouse   189 FGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFV 253

  Fly   260 QKCIQVRRESPAAQQRDDFLNYMLQLQEK-------KGLNAAELTSHTMTFLTDGFETTAQVLTH 317
            .:..:.|.:| ..:.|.|||..|:.....       |.|:..|:|:.::.|:..|:|||:..|:.
Mouse   254 NRMKESRLDS-KQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSF 317

  Fly   318 TLLFLARNPKEQMKLREEI-----GTAELTFEQISELPFTEACIHETLRIFSPVLAARKVVTEPC 377
            ||..||.:|..|.||:|||     ..|..|::.:.|:.:.:..::||||::.......:...:..
Mouse   318 TLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDV 382

  Fly   378 ELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFLNINGGAKKYRDQGLFFGFGDG 442
            ||   |||.:.  .|..|:||..|||||||::.||:.|:||||...|.|:   .|..|:..||.|
Mouse   383 EL---NGVYIP--KGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGS---IDPYLYMPFGIG 439

  Fly   443 PRICPGMRFSLTQIKAALVEIVRNFDIKVNPKTR 476
            ||.|.||||:...:|.||.::::||..:...:|:
Mouse   440 PRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	121/430 (28%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	122/433 (28%)