DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28d1 and Cyp9f3

DIOPT Version :9

Sequence 1:	NP_608912.1	Gene:	Cyp28d1 / 33749	FlyBaseID:	FBgn0031689	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001350862.1	Gene:	Cyp9f3 / 3772405	FlyBaseID:	FBgn0038034	Length:	433	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	118/518 - (22%)
Similarity:	205/518 - (39%)	Gaps:	113/518 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ALFVIAAILALIYVFLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQYKNTD 71
            |||.||.  ||.|.:.:.|..::|.|||...|...::|:...:|.:||.::..:.::|.: ..:.
  Fly     7 ALFAIAT--ALFYRWASANNDFFKDRGIAYEKPVLYLGNMAGMFLRKRAMLDIVCDLYTK-GGSG 68

  Fly    72 SIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSF--HDNEMAKFTDSKTDP-----ILANNPFVLTG 129
            ...|:|..|.|.|||..|:...:|.:.||..|  |.||..  |.|..||     :.:::.|.:..
  Fly    69 KFFGIFAQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFD--TSSDDDPHDMSNLFSSSLFSMRD 131

  Fly   130 EAWKERRAEVTPGLSANRVKAAYPVSLRVCKKFVEYIRRQSLMAPAQGLNAKDLCLCYTTEVISD 194
            ..||:.|:.::|..:.::::..:.:..:|.|:.|:.:::.........|:.||.|..:|.:||:.
  Fly   132 ARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIAS 196

  Fly   195 CVLGISAQSFTDNPTPMVGMTKRV----FEQSFGFIFYTVVANLWPPITKFYSVSLFAKDVAAFF 255
            ...|:...||.|.......|.|::    |.|:..||....:.:|    .|...|.:|.:....:|
  Fly   197 TAFGLQVNSFKDRENTFYQMGKKLTTFTFLQNMKFILLFALKSL----NKILKVEIFDRKSTQYF 257

  Fly   256 YDLMQKCIQVRRESPAAQQRDDFLNYMLQLQ-----EKKGLNAA------ELTSHTMTFLTDGFE 309
            ..|:...::.|:|....  |.|.:|.:::.:     ||...:|.      ::.:....|...|||
  Fly   258 VRLVLDAMKYRQEHNIV--RPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFE 320

  Fly   310 TTAQVLTHTLLFLARNPKEQMKLREEIGTAELTFEQISELPFTEACIHETLRIFSPVLAARKVVT 374
            |:|.::..|...|..|...|.:|.||:...:...|. .||.:.:..:.|.||.:.|.:|    ..
  Fly   321 TSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEG-KELKYLDQVVSEVLRKWPPAIA----FD 380

  Fly   375 EPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFLNINGGAKKYRDQGLFFGF 439
            ..|   ||...:|                   .||.                .|.||       |
  Fly   381 REC---NKEAKAV-------------------IYYL----------------LKDYR-------F 400

  Fly   440 GDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNPKTRKDNEIDDTYFMPALKGGVWLDFVERN 502
            ....:.|..:                              |:..:.|..:.|||.|:..|:||
  Fly   401 APAKKSCIPL------------------------------ELISSGFQLSPKGGFWIKLVQRN 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	p450	35..477	CDD:278495	96/463 (21%)
Cyp9f3	NP_001350862.1	p450	36..>388	CDD:325183	88/368 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460892
Domainoid	1	1.000	88	1.000	Domainoid score	I2119
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	7	7.000