Protein Alignment Cyp28d1 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 138/523 - (26%)
• Similarity: 230/523 - (43%)
• Gaps: 92/523 - (17%)

  Fly     9 FVIAAILALIYVFLT---WNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQYKNT 70
            ||:|...::....||   |.::||.::|:...:..||||....:...:...:..:.|..::|
 Worm     5 FVLAVTFSIFLGILTYYLWIWTYWMRKGVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKY--- 66

  Fly    71 DSIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILAN-------NPFVLT 128
            ..:.|........|:|..|...|:|:|..|.:|:..        |.:||..|       :.....
 Worm    67 GKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGR--------KLNPIQGNPEKEQRVHLLAAQ 123

  Fly   129 GEAWKERRAEVTPGLSANRVKAAYPVSLRVCKKFVE--------YIRRQSLMAPAQGLNAKDLCL 185
            |..||..|.     :|:.....|   ||:..|:.||        :|.:|:  |..:.::......
 Worm   124 GYRWKRLRT-----ISSQSFSNA---SLKKMKRTVEDSALELLRHIEKQT--AGGEQIDMLRFYQ 178

  Fly   186 CYTTEVISDCVLGISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWPPITKFYSVSLFA-K 249
            .||.:||....:|.:......|  |:|.:.:.:|..|...:.  ::..::|||.:|.....|. .
 Worm   179 EYTMDVIGRFAMGQTDSMMFKN--PIVNVVREIFCGSRKNLM--LICQVFPPIGQFIRDLTFKFP 239

  Fly   250 DVAAF-FYDLMQKCIQVR-----RESPA-----------------------AQQRDDFLNYMLQL 285
            .:.|| .|.:||..:..|     ||..|                       |:.|:||....|::
 Worm   240 RIPAFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKI 304

  Fly   286 QEKKGLNAAELTSHTMTFLTDGFETTAQVLTHTLLFLARNPKEQMKLREEI----GTAELTFEQI 346
              .|.|:|.|:......||..||:|||..|::....||.|||.|.|:.|||    ||:|:.||::
 Worm   305 --TKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGTSEVEFEKL 367

  Fly   347 SELPFTEACIHETLRIF--SPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYY 409
            ..|.:.:..|.|.||::  :.:..:||.:    :.|..||  ||:..|..|.:...:||:||:.:
 Worm   368 GRLKYMDCVIKEALRLYPLASISNSRKCM----KTTTVNG--VKIEAGVYVQMDTWSLHYDPELW 426

  Fly   410 -EEPQSFKPERFLNINGGAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNP 473
             |:.:.|||||:    ...:....:|.:..||.|||.|.|||.::.:.|..|..:::|:..:...
 Worm   427 GEDVKEFKPERW----STDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGN 487

  Fly   474 KTR 476
            |||
 Worm   488 KTR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	123/460 (27%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	124/463 (27%)