Protein Alignment Cyp28d1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 145/558 - (25%)
• Similarity: 235/558 - (42%)
• Gaps: 105/558 - (18%)

  Fly     7 ALFVIAAILALIYV--FLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQYKN 69
            |:..:|.:.::|.|  |..|.:||||:|||.....:|.:||...:.:.:......:.|..:||
 Worm     2 AIIFLAILTSIIGVLSFYLWTWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWTKQY-- 64

  Fly    70 TDSIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILAN-------NPFVL 127
             ..:.|:.:.....|:::.|:...:::|..:    ||    |...|.:||..:       |.|..
 Worm    65 -GKVYGITEGLSRTLVISDPDLVQEVFVKQY----DN----FFGRKLNPIQGDPNKDKRVNLFSS 120

  Fly   128 TGEAWKERRAEVTPGLSANRVKAAYPVSLRVCKKFVE--------YIRRQSLMAPAQGLNAKDLC 184
            .|..||..|...:|..|.|        |||..|..||        :|.:.:  ...|.::..|..
 Worm   121 QGHRWKRLRTISSPTFSNN--------SLRKLKTTVEECAVELLRHIEQHT--DGGQPIDLLDFY 175

  Fly   185 LCYTTEVISDCVLG-ISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLW-PPITKFYSVSL- 246
            ..:|.:||....:| ..:|.|.:   |::...:.||.:....:|.:.....| .||.:....||
 Worm   176 QEFTLDVIGRIAMGQTDSQMFKN---PLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLP 237

  Fly   247 -FAKDVAAFFYDLMQKCIQVRRESPAAQQR-----------------DDFLNYMLQLQE------ 287
             ..|:.|...         :|..|.|.:||                 .||::..|..:.
 Worm   238 NIVKNPAVHV---------IRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELE 293

  Fly   288 ------KKG------LNAAELTSHTMTFLTDGFETTAQVLTHTLLFLARNPKEQMKLREEI---- 336
                  |.|      |...|:......||..||:|||..|:::...||.:||.|.||:|||
 Worm   294 NNEDFTKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDREC 358

  Fly   337 GTAELTFEQISELPFTEACIHETLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNA 401
            ...|:||:|:|:|.:.|..|.||||:: |:.|...  :..|....|.| :.::..|..::.....
 Worm   359 ADPEVTFDQLSKLKYMECVIKETLRMY-PLGALAN--SRCCMRATKIG-NYEIDEGTNILCDTWT 419

  Fly   402 LHHDPQYY-EEPQSFKPERFLNINGGAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVR 465
            ||.|...: |:.:.|||||:   ..|.:.:..:|.:..||.|||.|.|||.:..:.|..|..|:|
 Worm   420 LHSDKSIWGEDAEEFKPERW---ESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILR 481

  Fly   466 NFDIKVNPKTRKDNE-IDDTYFMPALKGGVWLDFVERN 502
            .:.::|..||:...: |......|.   .|||:...|:
 Worm   482 KYTLEVCNKTQIPLKLIGSRTTQPE---SVWLNLTPRD 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	122/485 (25%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	124/486 (26%)