Protein Alignment Cyp28d1 and Cyp51

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 504
• Identity: 107/504 - (21%)
• Similarity: 193/504 - (38%)
• Gaps: 94/504 - (18%)

  Fly     4 ISTALFVIAAILALIYVFLTWNFSYWKKRGIPT-AKSWPFVGSFPSVFTQK-----RNVVYDIDE 62
            :||.|...|..|:|:|:|   ..:......:|. |||.|.:.| |..|...     ::.:..::.
Mouse    27 LSTLLIACAFTLSLVYLF---RLAVGHMVQLPAGAKSPPHIYS-PIPFLGHAIAFGKSPIEFLEN 87

  Fly    63 IYEQYKNTDSIVGVFQTRIPQLMVTTPEYAHKIYVSD-----FRSFHDNEMAKFTDSK-TDPILA 121
            .||:|....|...|.:|           :.: :..||     |.|.:::..|:....: |.|:..
Mouse    88 AYEKYGPVFSFTMVGKT-----------FTY-LLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFG 140

  Fly   122 NN-PFVLTGEAWKERRAEVTPGLSANRVKAAYPVSLRVCKKF------------VEYIRRQSLMA 173
            .. .:.:....:.|::..:..||:....|...|:..:..|::            .|.:....::.
Mouse   141 KGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWGESGERNVFEALSELIILT 205

  Fly   174 PAQGLNAKDLCLCYTTEVISDCVLGISAQSFTDNPTPMVGMTKRVFEQSFGFIFYTVVANLWPPI 238
            .:..|:.|::......:|         ||.:.|    :.|          ||.....:...|.|:
Mouse   206 ASHCLHGKEIRSQLNEKV---------AQLYAD----LDG----------GFTHAAWLLPAWLPL 247

  Fly   239 TKFYSVSLFAKDVAAFFYDLMQKCIQVRR--ESPAAQQRDDFLNYMLQLQEKKG--LNAAELTSH 299
            ..|.......:::...||    |.||.||  :.||    :|.|..:|....|.|  |...|::..
Mouse   248 PSFRRRDRAHREIKNIFY----KAIQKRRLSKEPA----EDILQTLLDSTYKDGRPLTDEEISGM 304

  Fly   300 TMTFLTDGFETTAQVLTHTLLFLARNP--KEQMKLREEIGTAE----LTFEQISELPFTEACIHE 358
            .:..|..|..|::........|||::.  :|:..|.::....|    ||::|:.:|...:.||.|
Mouse   305 LIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDLNLLDRCIKE 369

  Fly   359 TLRIFSPVLAARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFLNI 423
            |||:..|::...::...|     :......:.||..|.:...........:.|...|.|:|:|..
Mouse   370 TLRLRPPIMTMMRMAKTP-----QTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQD 429

  Fly   424 N-GGAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVR--NFDI 469
            | ...:|:    .:..||.|...|.|..|:..|||.....::|  .||:
Mouse   430 NPASGEKF----AYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	88/433 (20%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	91/439 (21%)