Protein Alignment Cyp28d1 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 541
• Identity: 119/541 - (21%)
• Similarity: 217/541 - (40%)
• Gaps: 115/541 - (21%)

  Fly    10 VIAAILALIYVFLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQYKNTDSIV 74
            |:..:|.|:.....:....|..:......|.||...|..   :|.....::.||....:|
Mouse    24 VLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGH---EKFKGDQELQEIVSCIEN----- 80

  Fly    75 GVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILANNPF------------VL 127
              |.:..|:..     :..|.|:    :.:|.:..|....::|| .||..:            :|
Mouse    81 --FPSAFPRWF-----WGSKAYL----TVYDPDYMKVILGRSDP-KANGAYRLLAPWIGYGLLLL 133

  Fly   128 TGEAWKERRAEVTPGLSANRVK-----AAYPVSLRVCK--------KFVEYIRRQSLMAPAQGLN 179
            .|:.|.:.|..:||....:.:|     .|..:.|.:.|        ..:|..:..|||
Mouse   134 NGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLM------- 191

  Fly   180 AKDLCLCYTTEVISDCVLGISAQSFTDNPTPMVGMTKRVFEQSFG---FIFYTVVANLW---PPI 238
                    |.:.:..|       :|:...:..|....|.:.|:.|   .:|::.|.|::   ..|
Mouse   192 --------TLDTVMKC-------AFSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTI 241

  Fly   239 TKFYSVSLFAKDVAAFFYDLMQKCIQVRR---------ESPAAQQRDDFLNYML--QLQEKKGLN 292
            .|..|....||......:|.....|::|:         |....::|.|||:.:|  :::....::
Mouse   242 YKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMS 306

  Fly   293 AAELTSHTMTFLTDGFETTAQVLTHTLLFLARNPKEQMKLREEIGT-----AELTFEQISELPFT 352
            ..:|.:...||:.:|.:|||..::.....||.:|..|.:.|||:.:     :.:|::.:.::|:|
Mouse   307 DKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYT 371

  Fly   353 EACIHETLRIFSPVLA-ARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFK 416
            ..||.|.||::.||.. .|::.|   .:|..:|.|  |..|..|.:.:..|||:|:.:..|:.|.
Mouse   372 TMCIKEALRLYPPVPGIVRELST---SVTFPDGRS--LPKGVQVTLSIYGLHHNPKVWPNPEVFD 431

  Fly   417 PERFLNINGGAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNPKTRKDNEI 481
            |.||     .....|....|..|..|.|.|.|.:|:::::|..:...:..|::..:| ||..
Mouse   432 PSRF-----APDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDP-TRVP--- 487

  Fly   482 DDTYFMPAL------KGGVWL 496
                 ||..      |.|::|
Mouse   488 -----MPLARLVLKSKNGIYL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	107/479 (22%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	110/491 (22%)