Protein Alignment Cyp28d1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_608912.1
• Gene: Cyp28d1 / 33749
• FlyBaseID: FBgn0031689
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 488
• Identity: 145/488 - (29%)
• Similarity: 247/488 - (50%)
• Gaps: 36/488 - (7%)

  Fly     4 ISTALFVIAAI-LALIYVFLTWNFSYWKKRGIPTAKSWPFVGSFPSVFTQKRNVVYDIDEIYEQY 67
            :|...:|:.|| |.|:|.:.|.....:||:|||..|..||:|:..:.:  |....:|: |.|::|
Mouse     7 LSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYY--KGLWKFDM-ECYKKY 68

  Fly    68 KNTDSIVGVFQTRIPQLMVTTPEYAHKIYVSDFRSFHDNEMAKFTDSKTDPILANNPFVLTGEAW 132
            ..|   .|:|..:.|.|.||.||....:.|.:..|...|.    .|.....|::....:...:.|
Mouse    69 GKT---WGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNR----RDFGPVGIMSKAISISKDDEW 126

  Fly   133 KERRAEVTPGLSANRVKAAYPVSLRVCKKFVEYIRRQSLMAPAQGLNAKDLCLCYTTEVISDCVL 197
            |..||.::|..::.::|..:||..:.....|:|:|:::  ...:.:..||:...|:.:||:....
Mouse   127 KRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKA--KKGKPVTMKDVLGAYSMDVITSTSF 189

  Fly   198 GISAQSFTDNPTPMVGMTKRVFEQSF--GFIFYTVVANLWPPITKFYSVSLFAKDVAAFFYDLMQ 260
            |::..|..:...|.|...|::....|  ..:|..|:.....|:.:..::.:|.||...||...:.
Mouse   190 GVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVD 254

  Fly   261 KCIQVRRESPAAQQRDDFLNYMLQLQEK-------KGLNAAELTSHTMTFLTDGFETTAQVLTHT 318
            :..:.|.:| ..:.|.|||..|:.....       |.|:..|:|:.::.|:..|:|||:..|:.|
Mouse   255 RMKESRLDS-KQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTSSTLSFT 318

  Fly   319 LLFLARNPKEQMKLREEI-----GTAELTFEQISELPFTEACIHETLRIFSPVLAARKVVTEPCE 378
            |..||.:|..|.||::||     ..|..|::.:.|:.:.:..::||||::.......:|..:..|
Mouse   319 LHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVE 383

  Fly   379 LTNKNGVSVKLRPGDVVIIPVNALHHDPQYYEEPQSFKPERFLNINGGAKKYRDQGLFFGFGDGP 443
            |   |||.:.  .|..|:||..|||||||::.||:.|:||||...|.|:   .|..::..||:||
Mouse   384 L---NGVYIP--KGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGS---IDPYVYLPFGNGP 440

  Fly   444 RICPGMRFSLTQIKAALVEIVRNFDIKVNPKTR 476
            |.|.||||:|..:|.||.:|::||..:...:|:
Mouse   441 RNCLGMRFALMNMKLALTKIMQNFSFQPCKETQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d1	NP_608912.1	CYP6-like	69..495	CDD:410679	123/422 (29%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	124/425 (29%)