DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28d2 and CYP711A1

DIOPT Version :9

Sequence 1:	NP_608911.1	Gene:	Cyp28d2 / 33748	FlyBaseID:	FBgn0031688	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_565617.2	Gene:	CYP711A1 / 817157	AraportID:	AT2G26170	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	120/528 - (22%)
Similarity:	211/528 - (39%)	Gaps:	71/528 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYEKYKDTDN 72
            |:..||...:|.|...:..: |....:......|.||..|.:      ..|..|......|....
plant    21 LIAFLTFAAVVIVIYLYRPS-WSVCNVPGPTAMPLVGHLPLM------AKYGPDVFSVLAKQYGP 78

  Fly    73 MVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLTGDE-WKERR 136
            :......|.|.:::...|...::....|:...|   |:..:..:...|.......|.|: |.:.|
plant    79 IFRFQMGRQPLIIIAEAELCREVGIKKFKDLPN---RSIPSPISASPLHKKGLFFTRDKRWSKMR 140

  Fly   137 SEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAM--DLSLCYTTEVVSDCGLG- 198
            :.|:....|:.:.::.|...|       :|........|:..|.:  :|.|..||:::.....|
plant   141 NTILSLYQPSHLTSLIPTMHS-------FITSATHNLDSKPRDIVFSNLFLKLTTDIIGQAAFGV 198

  Fly   199 ------------VSAQSFTDTPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKVRKFY-----SVPF 246
                        |....|.:........:|...:.|...|...::..|.:..|:..     ::.:
plant   199 DFGLSGKKPIKDVEVTDFINQHVYSTTQLKMDLSGSLSIILGLLIPILQEPFRQVLKRIPGTMDW 263

  Fly   247 FNKETEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEK----KGLHT-DNILINTMTFILDG 306
            ..::|.......:...::.|.::.|....|||:.:|:.:|.    |.:.| |.|...|...:|.|
plant   264 RVEKTNARLSGQLNEIVSKRAKEAETDSKDFLSLILKARESDPFAKNIFTSDYISAVTYEHLLAG 328

  Fly   307 FETTALVLAHIMLMLGRNPEEQDKVRKEI---GSADL---TFDQMSELPHLDACIYETLRLF--S 363
            ..|||..|:.::.::..:.:.:.::.:||   |:.||   ..|...:.|:||..|.|.:|.:  |
plant   329 SATTAFTLSSVLYLVSGHLDVEKRLLQEIDGFGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVS 393

  Fly   364 PQVAARKLVTEPFEFANKNGRTVHLKP-GDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGM 427
            |.||.        |.|.:.....:|.| |..|.:.:..|..||:.:.:|..|||||| :.||...
plant   394 PLVAR--------ETAKEVEIGGYLLPKGTWVWLALGVLAKDPKNFPEPEKFKPERF-DPNGEEE 449

  Fly   428 KSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTRSDNQIDDTFFMATLKG 492
            | :|....::.||.|||.|.|.||||.::|..|:.:.||:..:.:.:.....|:|         .
plant   450 K-HRHPYAFIPFGIGPRACVGQRFALQEIKLTLLHLYRNYIFRHSLEMEIPLQLD---------Y 504

  Fly   493 GIYLDFKD 500
            ||.|.||:
plant   505 GIILSFKN 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	p450	38..475	CDD:299894	107/471 (23%)
CYP711A1	NP_565617.2	cytochrome_P450	75..515	CDD:425388	107/467 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786853at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.920