Protein Alignment Cyp28d2 and cyp17a2

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001099140.1
• Gene: cyp17a2 / 796487
• ZFINID: ZDB-GENE-100822-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 565
• Identity: 116/565 - (20%)
• Similarity: 211/565 - (37%)
• Gaps: 171/565 - (30%)

  Fly     1 MCPVTT---FLVLVLTLLVLVYVFLTWNFNYWRKRGIKTA-------PTWPFVGSF--------P 47
            ||.|:.   |..|:|.||:||...|         .|:.::       |..|.:||.        |
Zfish     1 MCSVSVCVCFSALLLLLLLLVRRLL---------EGVGSSSVSFPCLPRLPLLGSLLHLRSNLPP 56

  Fly    48 SIFTRKRNIAYDIDDIYEKYKDTDNMVGVFTTRVPQLLVMCPE--YIHKIYATDFRSFHNNEWRN 110
            .:...:.:..|            ..:.|::..  |.|.::..|  .:.::..        ...|.
Zfish    57 HLLFTQLSSQY------------GPLFGLYAG--PHLTLVVSEIGLVREVLL--------QRGRE 99

  Fly   111 FVNK----KTDMILGNNPFVLTGDE---WKERRSEIMPALS-----PNRVKA-VYPVSQSVCKKF 162
            |..:    .||::......:...|.   ||..|..:..:.:     .|:::. |...:.|:|::.
Zfish   100 FAGRPKMVTTDLLTQGGKDIAFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEEL 164

  Fly   163 VEYIRRQQQMATSEGLDAMDLSLCYTTEVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSF-EFI 226
                    |....:..|...:.:...|.|:  |.| |.:.|:..:...|..:|:  :|... :.|
Zfish   165 --------QACRGQSSDLSVVLMRAVTNVI--CRL-VFSSSYQPSDPELQTVIQ--YNDGIVQTI 216

  Fly   227 FYSVVTNL--WQKVRKFYSVPFFNKETEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEKKG 289
            ....:.::  |.::       |.||:     |..::.|:::|         |.|.|...|:.||.
Zfish   217 ARGGLVDIFPWLRI-------FPNKD-----LKRLKECVSIR---------DQLLYKKLLEHKKS 260

  Fly   290 L--------------------------HTDNILINTMTFILDGFETTALVLAHIMLMLGRNPEEQ 328
            |                          ..|::|:........|.|||:..|...:..|..:|:.|
Zfish   261 LTPGEPRDLLDALLIGQQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQ 325

  Fly   329 DKVRKEIGSADLTFDQ---MSELPH---LDACIYETLR------LFSPQVAARKLVTEPFEFANK 381
            ::|:.|:... :..|:   :|:.||   |||.:.|.:|      :..|.||        .:..:.
Zfish   326 ERVQAELDEC-VGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVA--------MQDTSL 381

  Fly   382 NGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHC 446
            .|.:|  ..|..|.:.:.|:||||::::.|..|.||||||.:|    ..:.:..:|.||.|||.|
Zfish   382 GGHSV--PKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEPSG----KKKTQSSFLPFGAGPRVC 440

  Fly   447 PGMRFALTQL-----------------KAALVEILRNFEIKVNPK 474
            .|...|..:|                 :|:|.::...|.:.:.|:
Zfish   441 VGESLARIELFLFVSRPLQRFSFSCPSEASLPDLQGRFGVVLQPE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	98/474 (21%)
cyp17a2	NP_001099140.1	CYP17A1	67..489	CDD:410766	99/490 (20%)