Protein Alignment Cyp28d2 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 546
• Identity: 121/546 - (22%)
• Similarity: 213/546 - (39%)
• Gaps: 110/546 - (20%)

  Fly     4 VTTFLVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPF---------------------VGSFP 47
            |.:...|:|.|:..|.|:|   ...|..:.::..|:.||                     :.:||
Mouse    21 VASVFCLLLLLVKAVQVYL---HRKWLLKALQQFPSPPFHWFFGHEQFKGDQELQEIVSCIENFP 82

  Fly    48 SIFTRKRNIAYDIDDIYEKYKDTDNMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFV 112
            |.|.|                       .|......|.|..|:|:..|..      .::...|..
Mouse    83 SAFPR-----------------------WFWGSKAYLTVYDPDYMKVILG------RSDPKANGA 118

  Fly   113 NKKTDMILGNNPFVLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEG 177
            .:.....:|....:|.|..|.:.|..:.||..       |.:.::..|...:.||  ..:...|.
Mouse   119 YRLLAPWIGYGLLLLNGQSWFQHRKMLTPAFH-------YDILKTYVKNMADSIR--LMLDKWER 174

  Fly   178 LDAMDLSL-------CYTTEVVSDCGLGVSAQSFTD-TPTPLLKMIKRVFNTSFEFIFYSVVTNL 234
            |...|.|:       ..|.:.|..|..........| .....|:.|..:.|     :.:|.|.|:
Mouse   175 LAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNN-----LVHSRVRNM 234

  Fly   235 WQKVRKFYSVP----FFNKETEVFFLDIIRRCITLRLEK----------PEQQRDDFLNYML--Q 283
            :.:....|.:.    ..|:..::.. |.....|.:|.::          .:::|.|||:.:|  :
Mouse   235 FHQNDTIYKLSSNGRLSNQACQLAH-DHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFAR 298

  Fly   284 LQEKKGLHTDNILINTMTFILDGFETTALVLAHIMLMLGRNPEEQDKVRKEIGS-----ADLTFD 343
            ::.:..:...::.....||:::|.:|||..::.|...|..:||.|.:.|:|:.|     :.:|:|
Mouse   299 MENEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWD 363

  Fly   344 QMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYY 408
            .:.::|:...||.|.|||:.|..:..:.::....|.:    ...|..|..||:.:..|||:|:.:
Mouse   364 HLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPD----GCSLPKGVQVTLSIYGLHHNPKVW 424

  Fly   409 EDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNP 473
            .:|..|.|.||...      |.|....:|.|..|.|:|.|.:||:::||..:...|..||:..:|
Mouse   425 PNPEVFDPSRFAPD------SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDP 483

  Fly   474 KTRSDNQIDDTFFMATLKGGIYLDFK 499
             ||....:  ..|:...|.||||..|
Mouse   484 -TRVPMSL--ARFVLKSKNGIYLHLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	101/449 (22%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	108/489 (22%)