Protein Alignment Cyp28d2 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 502
• Identity: 133/502 - (26%)
• Similarity: 238/502 - (47%)
• Gaps: 76/502 - (15%)

  Fly     9 VLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNI--------AYDIDDIYE 65
            ||::|.||..|::.|::...::|.||......|..|          ||        .:| ||.|:
Mouse    13 VLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFG----------NIINYLDGMWKFD-DDCYK 66

  Fly    66 KYKDTDNMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLTG- 129
            ||   ..:.|.:....|.|.:|.||.|..:...:..|.       |.|::        ||...|
Mouse    67 KY---GKIWGFYEGPQPILAIMDPEIIKIVLVKECYSV-------FTNRR--------PFGPVGF 113

  Fly   130 ----------DEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLS 184
                      :|||..|:.:.|..:.:::|.::|:.:......|..:||:::  ..|.::..|:.
Mouse   114 LKKSITISEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEE--KEEPINMKDIF 176

  Fly   185 LCYTTEVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSF--EFIFYSVVTNLWQKVRKFYSVPFF 247
            ..|:.:|::....||:..|..:...|.::.||::....|  .|:...|:......:.:..::..|
Mouse   177 GAYSMDVITGTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIF 241

  Fly   248 NKETEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEKKG------LHTDNILINTMTFILDG 306
            .:::..||...:::....||:..::.|.|||..|:..|..||      |....:...|:.||..|
Mouse   242 PRQSMNFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGG 306

  Fly   307 FETTALVLAHIMLMLGRNPEEQDKVRKEI-----GSADLTFDQMSELPHLDACIYETLRLFSPQV 366
            ::.|:..::.||..|..:|:.|.|::.||     ..|.:|:|.:.::.:||..:.|:|||:
Mouse   307 YDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVVNESLRLY---- 367

  Fly   367 AARKLVTEPFEFANKNGRT--VHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKS 429
               .:|:....|:.|:...  |.:..|.:|.||:..||.||:|:.:|..|.||||.:.|.|.:..
Mouse   368 ---PVVSRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDP 429

  Fly   430 YRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTR 476
            |    :|:.||:|||:|.||||||..:|.|:..:|:||.::...:|:
Mouse   430 Y----IYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	113/429 (26%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	115/437 (26%)