Protein Alignment Cyp28d2 and Cyp51

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 121/521 - (23%)
• Similarity: 189/521 - (36%)
• Gaps: 132/521 - (25%)

  Fly     4 VTTFLVLVLTLLVLVYVF-LTWNFNYWRKRGIKTAP----TWPFVGSFPSIFTRKRNIAYDIDDI 63
            ::|.|:.....|.|||:| |..........|.|:.|    ..||:|.  :|...|..|.: :::.
  Rat    27 LSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGH--AIAFGKSPIEF-LENA 88

  Fly    64 YEKYKDTDNMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLT 128
            ||||    ..|..||                                .|.|....:||::...|.
  Rat    89 YEKY----GPVFSFT--------------------------------MVGKTFTYLLGSDAAALL 117

  Fly   129 GDEWKE--RRSEIMPAL-SPNRVKAV-YPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLCYTT 189
            .:...|  ...|:...| :|...|.| |.|..:|   |:|     |:.....||:...... |.:
  Rat   118 FNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAV---FLE-----QKKILKSGLNIAHFKQ-YVS 173

  Fly   190 EVVSDC-----GLGVSAQSFTDTPTPLLKMIKRVFNTSFEFIFYS---------VVTNLWQKVRK 240
            .:..:.     ..|.|.:             :.||....|.|..:         :.:.|.:||.:
  Rat   174 IIEKEAKEYFKSWGESGE-------------RNVFEALSELIILTASHCLHGKEIRSQLNEKVAQ 225

  Fly   241 FYS------------------VPFFNKE-------TEVFFLDIIRRCITLRLEKPEQQRDDFLNY 280
            .|:                  :|.|.:.       ..:|:..|.:|    ||.|  :..:|.|..
  Rat   226 LYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKR----RLSK--EPAEDILQT 284

  Fly   281 MLQLQEKKG--LHTDNILINTMTFILDGFETTALVLAHIMLMLGRNPEEQDKV---RKEIGSAD- 339
            :|....|.|  |..|.|....:..:|.|..|::...|.:...|.|:...|||.   :|.:...|
  Rat   285 LLDSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDL 349

  Fly   340 --LTFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALH 402
              ||::|:.:|..||.||.|||||..|.:...::...|...|   |.|:  .||..|.:......
  Rat   350 PPLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVA---GYTI--PPGHQVCVSPTVNQ 409

  Fly   403 HDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNF 467
            .....:.:.|.|.|:|:|:.|....:.:    .|:.||.|...|.|..||..|:|.....:||.:
  Rat   410 RLKDSWVERLDFNPDRYLQDNPASGEKF----AYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLY 470

  Fly   468 E 468
            |
  Rat   471 E 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	100/446 (22%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	104/457 (23%)