Protein Alignment Cyp28d2 and Cyp3a18

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 135/484 - (27%)
• Similarity: 234/484 - (48%)
• Gaps: 40/484 - (8%)

  Fly     9 VLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYEKYKDTDNM 73
            ||:.|.|:|.|::.|::...::|.||......|..|   :||.....:....||.|:||   ..:
  Rat    13 VLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFG---TIFNYGDGMWKFDDDCYKKY---GKI 71

  Fly    74 VGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLT---GDEWKER 135
            .|.:....|.|.:|.||.|..:...:..|.       |.|::....:|.....:|   .:|||..
  Rat    72 WGFYEGPQPFLAIMDPEIIKMVLVKECYSV-------FTNRRCFGPMGFMKKAITMSEDEEWKRL 129

  Fly   136 RSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLCYTTEVVSDCGLGVS 200
            |:.:.|..:..::|.::|:.:......::.:||::  |..|.::..|:...|:.:|::....||:
  Rat   130 RTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREE--AKGEPINMKDIFGAYSMDVITGTSFGVN 192

  Fly   201 AQSFTDTPTPLLKMIKRV--FNTSFEFIFYSVVTNLWQKVRKFYSVPFFNKETEVFFLDIIRRCI 263
            ..|..:...|.::..|::  |.....|:...|:......:.:..:...|.:::..||...::...
  Rat   193 VDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTPIYEMLNFSIFPRQSMNFFKKFVKTMK 257

  Fly   264 TLRLEKPEQQRDDFLNYMLQLQEKKGLHTDNIL------INTMTFILDGFETTALVLAHIMLMLG 322
            ..||:..::.|.|||..|:..|..||..:...|      ...:.||..|::.|:..::.||..|.
  Rat   258 KNRLDSNQKSRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAIIFIFGGYDATSTSISFIMYELA 322

  Fly   323 RNPEEQDKVRKEI-----GSADLTFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFANKN 382
            ..|..|.|::.||     ..|.:|:|.:.|:.:||..:.|:|||:.......::..:..|.   |
  Rat   323 TRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDVEI---N 384

  Fly   383 GRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCP 447
            |  |.:..|.|||||:..||.:|:|:.:|..|.||||.:.|.|.:..|    |||.||:|||:|.
  Rat   385 G--VFIPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPY----VYLPFGNGPRNCI 443

  Fly   448 GMRFALTQLKAALVEILRNFEIKVNPKTR 476
            ||||||..:|.|::.:|:||.|:...||:
  Rat   444 GMRFALISMKLAVIGVLQNFNIQPCEKTQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	116/419 (28%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	118/427 (28%)