Protein Alignment Cyp28d2 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 115/513 - (22%)
• Similarity: 211/513 - (41%)
• Gaps: 89/513 - (17%)

  Fly     8 LVLVLTLLVLVYVFLTWNFNYWRKR---------GIKTAPTWPFVGSFPSIFTRKRNIAYDIDDI 63
            ::::.|:...:..|:  :::.||:.         ||...|.....|:...|..|...:.|:
 Worm     3 ILIISTIFFTIITFI--SYSIWRRHAIFKLRSSIGIPGPPVHWLWGNLNIIKDRVSRLGYN---- 61

  Fly    64 YEKYKDTDNMVGVFTTRV-PQLLVMCPEYIHKIYA--TDFRSFHNNEWRNFVNKKTDMILGNNPF 125
                 ||........|:. |...:.|...:|...:  .|.:......:.||.::.|..|.|.|..
 Worm    62 -----DTTQWHPTLHTKYGPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMTPDIFGMNQL 121

  Fly   126 --------VLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMD 182
                    ..||  ||..||.|.|..|..::||::....|....|:|.::  ::.::.:..|..:
 Worm   122 NQSLLQNTYATG--WKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEVLK--EKSSSGQKWDIFE 182

  Fly   183 LSLCYTTEVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSFEF---------IFYSVVTNLWQKV 238
            .....:.:::..|...:.:....|. |.|..:..|.|..:.:.         :....::.||:.:
 Worm   183 NFQSLSLDIIGKCAFAIDSNCQRDR-TDLFYVQARKFVGAVDLKKSWILPVSLILPELSWLWRFL 246

  Fly   239 RKFYSVPFFNKETEVFFLDIIRRCITL--RLEKPEQQRD--DFLNYMLQLQEKKGLHTDNILINT 299
            .||       .:.....|.:::..:.|  |....|...|  |.||.:::.:....:....::.|.
 Worm   247 YKF-------SDLSAAELPLVKGLVDLYDRRRAGEGGNDSTDLLNLLIRRETIGKMTQREVIENC 304

  Fly   300 MTFILDGFETTALVLAHIMLMLGRNPEEQDKVRKEI----GSADLTFDQMSELPHLDACIY-ETL 359
            ..|::.|:|||:..:.....:|...|..|.|:.:||    .:|.|.:|.:..:.:|| |:| |:|
 Worm   305 FAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKENAGLNYDSIHNMKYLD-CVYKESL 368

  Fly   360 RLFSPQVAARKLVTEPFEFANK---NGRTV--HLKPGDVVTIPVK--ALHHDPQYYEDPLTFKPE 417
            |.:.|..          .|.|:   |..|:  .:.|.| .|:.|:  .:|.:|..:|.|..|:||
 Worm   369 RFYPPTT----------HFTNRVCLNDMTIRGQIYPED-STLKVQPYTIHRNPANWESPDEFQPE 422

  Fly   418 RF--LESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNP 473
            ||  .|.....:|       ::.||.|||:|.|||||..:.|..:.::|..||:.:.|
 Worm   423 RFENWEEKSSSLK-------WIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELSLVP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	102/438 (23%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	101/432 (23%)