Protein Alignment Cyp28d2 and Cyp51

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 510
• Identity: 117/510 - (22%)
• Similarity: 187/510 - (36%)
• Gaps: 110/510 - (21%)

  Fly     4 VTTFLVLVLTLLVLVYVF-LTWNFNYWRKRGIKTAP----TWPFVGSFPSIFTRKRNIAYDIDDI 63
            ::|.|:.....|.|||:| |..........|.|:.|    ..||:|.  :|...|..|.: :::.
Mouse    27 LSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGH--AIAFGKSPIEF-LENA 88

  Fly    64 YEKYKD--TDNMVG-VFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRN---FVNKKTDMILGN 122
            ||||..  :..||| .||            |:....|........||..|   ...:.|..:.|.
Mouse    89 YEKYGPVFSFTMVGKTFT------------YLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGK 141

  Fly   123 N-PFVLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLC 186
            . .:.:....:.|::..|...|:....|...|:.:...|   ||.:...:.......:|:...:.
Mouse   142 GVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAK---EYFQSWGESGERNVFEALSELII 203

  Fly   187 YTTEVVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKVRKFYS-------- 243
            .|   .|.|..|              |.|:...|               :||.:.|:
Mouse   204 LT---ASHCLHG--------------KEIRSQLN---------------EKVAQLYADLDGGFTH 236

  Fly   244 ----------VPFFNKE-------TEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEKKG-- 289
                      :|.|.:.       ..:|:..|.:|    ||.|  :..:|.|..:|....|.|
Mouse   237 AAWLLPAWLPLPSFRRRDRAHREIKNIFYKAIQKR----RLSK--EPAEDILQTLLDSTYKDGRP 295

  Fly   290 LHTDNILINTMTFILDGFETTALVLAHIMLMLGRNPEEQDKV---RKEIGSAD---LTFDQMSEL 348
            |..:.|....:..:|.|..|::...|.:...|.::...|:|.   :|.:...|   ||:||:.:|
Mouse   296 LTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDL 360

  Fly   349 PHLDACIYETLRLFSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLT 413
            ..||.||.|||||..|.:...::...|...|   |.|:  .||..|.:...........:.:.|.
Mouse   361 NLLDRCIKETLRLRPPIMTMMRMAKTPQTVA---GYTI--PPGHQVCVSPTVNQRLKDSWAERLD 420

  Fly   414 FKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFE 468
            |.|:|:|:.|....:.:    .|:.||.|...|.|..||..|:|.....:||.:|
Mouse   421 FNPDRYLQDNPASGEKF----AYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	95/433 (22%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	100/446 (22%)