Protein Alignment Cyp28d2 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 542
• Identity: 129/542 - (23%)
• Similarity: 220/542 - (40%)
• Gaps: 98/542 - (18%)

  Fly     4 VTTFLVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYEKYK 68
            |.:.|.|:|.|:..|..:|   ...|..:..:..|:.||...|.                :||:|
Mouse    21 VASVLGLLLLLVKAVQFYL---HRQWLLKAFQQFPSPPFHWFFG----------------HEKFK 66

  Fly    69 DTDNMVGV------FTTRVPQ--------LLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMI 119
            ....:..:      |.:..|:        |.|..|:|:..|..      .::...|...:.....
Mouse    67 GDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILG------RSDPKANGAYRLLAPW 125

  Fly   120 LGNNPFVLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIR----RQQQMATSE-GLD 179
            :|....:|.|..|.:.|..:.||..       |.:.:...|...:.||    :.:::|..: .::
Mouse   126 IGYGLLLLNGQPWFQHRRMLTPAFH-------YDILKPYVKNMADSIRLMLDKWERLADQDSSIE 183

  Fly   180 AMDLSLCYTTEVVSDCGLGVSAQSFTD-TPTPLLKMIKRVFNTSFEFIFYSVVTNLWQK---VRK 240
            ........|.:.|..|..........| .....|:.|..:.|     :|:|.|.|::.:   :.|
Mouse   184 IFQHISLMTLDTVMKCAFSHKGSVQVDGNYRTYLQAIGDLNN-----LFHSRVRNIFHQNDTIYK 243

  Fly   241 FYSVPFFNKETEVFFLDIIRRCITLR---------LEK-PEQQRDDFLNYML--QLQEKKGLHTD 293
            ..|.....|:......|.....|.||         ||| .:::|.|||:.:|  :::....:...
Mouse   244 LSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDK 308

  Fly   294 NILINTMTFILDGFETTALVLAHIMLMLGRNPEEQDKVRKEIGS-----ADLTFDQMSELPHLDA 353
            ::.....||:.:|.:|||..::.|...|..:|:.|.:.|:|:.|     :.:|:|.:.::|:...
Mouse   309 DLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTM 373

  Fly   354 CIYETLRLFSPQVA-ARKL---VTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTF 414
            ||.|.|||:.|... .|:|   ||.|      :||:  |..|..||:.:..|||:|:.:.:|..|
Mouse   374 CIKEALRLYPPVPGIVRELSTSVTFP------DGRS--LPKGVQVTLSIYGLHHNPKVWPNPEVF 430

  Fly   415 KPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTRSDN 479
            .|.||...      |.|....:|.|..|.|:|.|.:||:::||..:...|..||:..:| ||...
Mouse   431 DPSRFAPD------SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDP-TRVPM 488

  Fly   480 QIDDTFFMATLKGGIYLDFKDL 501
            .:  ...:...|.||||..|.|
Mouse   489 PL--ARLVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	109/464 (23%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	111/467 (24%)