Protein Alignment Cyp28d2 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 492
• Identity: 137/492 - (27%)
• Similarity: 242/492 - (49%)
• Gaps: 53/492 - (10%)

  Fly     8 LVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYEKYKDTDN 72
            |||:..:|||:|.:.|.....::|:||......||:|:..:.:  |....:|: :.||||..|
Mouse    12 LVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYY--KGLWKFDM-ECYEKYGKT-- 71

  Fly    73 MVGVFTTRVPQLLVMCPEYIHKIYATD-FRSFHNNEWRNFVNKKTDM----ILGNNPFVLTGDEW 132
             .|:|..::|..::..||.|..:...: |..|.|.:         |.    |:..:..:...:||
Mouse    72 -WGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQ---------DFFPVGIMSKSISLAKDEEW 126

  Fly   133 KERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLCYTTEVVSDCGL 197
            |..|:.:.|..:...:|.::||.:......|:|:|  |:....:.:...|:...|:.:|:.....
Mouse   127 KRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLR--QEAEKGKPVAVKDVLGAYSMDVIISTTF 189

  Fly   198 GVSAQSFTDTPTPLLKMIKRVFN------TSFEFIFYSVVTNLWQKVRKFYSVPFFNKETEVFFL 256
            ||:..|..:...|.::..|:|..      .|.....:..:|.:::.:    ::..|.|::..||.
Mouse   190 GVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEML----NICMFPKDSIEFFK 250

  Fly   257 DIIRRCITLRLEKPEQQRDDFLNYMLQLQEK-------KGLHTDNILINTMTFILDGFETTALVL 314
            ..:.|....||:..::.|.||:..|::...|       |.|....|...::.||..|:|||:.:|
Mouse   251 KFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQSIIFIFAGYETTSSIL 315

  Fly   315 AHIMLMLGRNPEEQDKVRKEI-----GSADLTFDQMSELPHLDACIYETLRLFSPQVAARKLVTE 374
            :..:..|..:|:.|.|:::||     ..|..|:|.:..:.:||..:.|||||:......:::..:
Mouse   316 SFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKK 380

  Fly   375 PFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAF 439
            ..|.   ||  :::..|..|.||...||||||::.:|..|:||||.:.|.|.:..|    |||.|
Mouse   381 DVEI---NG--IYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDPY----VYLPF 436

  Fly   440 GDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTR 476
            |:|||:|.||||||..:|.||:::|:||..:...:|:
Mouse   437 GNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	116/426 (27%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	119/434 (27%)