Protein Alignment Cyp28d2 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 492
• Identity: 143/492 - (29%)
• Similarity: 237/492 - (48%)
• Gaps: 68/492 - (13%)

  Fly     9 VLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAY-------DIDDIYEK 66
            :|:.|.|||:|::.|.:...::|.||......||:|:.         :||       || ..::|
Mouse    13 MLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTI---------LAYQKGFWECDI-QCHKK 67

  Fly    67 YKDTDNMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNF----VNKKTDMILGNNPFVL 127
            |   ..|.|::..|.|.|.:..|:.|..:...:..|...|. |.|    :.||...|..|
Mouse    68 Y---GKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNR-RRFGPVGILKKAISISEN----- 123

  Fly   128 TGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEG--LDAMDLSLCYTTE 190
              :|||..|:.:.|..:..|:|.::|    :..:|.:.:.|..:....||  ....|:...|:.:
Mouse   124 --EEWKRIRALLSPTFTSGRLKEMFP----IINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMD 182

  Fly   191 VVSDCGLGVSAQSFTDTPTPLLKMIKRVFNTS-FEFIFYSV-----VTNLWQKVRKFYSVPFFNK 249
            |::....||:..|..:...|.::.||::.... |:.:|.||     :|.::..:    :|..|.:
Mouse   183 VITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDAL----NVSLFPR 243

  Fly   250 ETEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQ------EKKGLHTDNILINTMTFILDGFE 308
            :...||...:.|....|:::.|:||.|||..|:..|      ..|.|....|:..::.||..|:|
Mouse   244 DVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSVIFIFAGYE 308

  Fly   309 TTALVLAHIMLMLGRNPEEQDKVRKEI-----GSADLTFDQMSELPHLDACIYETLRLFSPQVAA 368
            ||:..|:..:.:|..:|:.|.|::.||     ..|..|:|.:.::.:||..:.|||||:......
Mouse   309 TTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRL 373

  Fly   369 RKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDR 433
            .::.....|.   ||  :.:..|.||.||..|||.||:|:.:|..|:||||.:.|...:..|
Mouse   374 ERVCKTDVEI---NG--LFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPY--- 430

  Fly   434 GVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIK 470
             :||.||.|||:|.||||||..:|.|||.:|:||.::
Mouse   431 -MYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQ 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	123/420 (29%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	126/428 (29%)