Protein Alignment Cyp28d2 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 544
• Identity: 128/544 - (23%)
• Similarity: 218/544 - (40%)
• Gaps: 102/544 - (18%)

  Fly     4 VTTFLVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFVGSFPSIFTRKRNIAYDIDDIYEKYK 68
            |.:.|.|:|.|:..|..:|   ...|..:.::..|:.||...|.                :|::|
Mouse    21 VASVLGLLLLLVKAVQFYL---HRKWLLKALQQFPSPPFHWFFG----------------HEQFK 66

  Fly    69 DTDNMVGV------FTTRVP--------QLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMI 119
            ....:..|      |.:..|        .|.|..|:|:..|..      .::...|.:.:.....
Mouse    67 GEQELKEVVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILG------RSDPKANGIYRLLAPW 125

  Fly   120 LGNNPFVLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLS 184
            :|....:|.|..|.:.|..:.||..       |.:.:...|...:.||  ..:...|.|...|.|
Mouse   126 IGYGLLLLNGQPWFQHRRMLTPAFH-------YDILKPYVKNMADSIR--LMLDKWERLAGQDSS 181

  Fly   185 L-------CYTTEVVSDCGLGVSAQSFTD-TPTPLLKMIKRVFNTSFEFIFYSVVTNLWQKVRKF 241
            :       ..|.:.|..|..........| .....|:.|..:.|     :|:|.|.|::.:....
Mouse   182 IEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNN-----LFHSRVRNIFHQNDTI 241

  Fly   242 YSVPF---FNKETEVFFLDIIRRCITLRLEK----------PEQQRDDFLNYML--QLQEKKGLH 291
            |.:..   ..|:......|.....|.:|.::          .:::|.|||:.:|  :::....:.
Mouse   242 YRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENGDSMS 306

  Fly   292 TDNILINTMTFILDGFETTALVLAHIMLMLGRNPEEQDKVRKEIGS-----ADLTFDQMSELPHL 351
            ..::.....||:.:|.:|||..::.|...|..:||.|.:.|:|:.|     :.:|:|.:.::|:.
Mouse   307 DKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYT 371

  Fly   352 DACIYETLRLFSPQVA-ARKL---VTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPL 412
            ..||.|.|||:.|... .|:|   ||.|      :||:  |..|..||:.:..|||:|:.:.:|.
Mouse   372 TMCIKEALRLYPPVPGIVRELSTSVTFP------DGRS--LPKGVQVTLSIYGLHHNPKVWPNPE 428

  Fly   413 TFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTRS 477
            .|.|.||...      |.|....:|.|..|.|:|.|.:||:::||..:...|.:||:..:| ||.
Mouse   429 VFDPSRFAPD------SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLPDP-TRV 486

  Fly   478 DNQIDDTFFMATLKGGIYLDFKDL 501
            ...:  ...:...|.||||..|.|
Mouse   487 PEPL--ARIVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	109/466 (23%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	111/469 (24%)