DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5828 and Pank1

DIOPT Version :9

Sequence 1:	NP_001260085.1	Gene:	CG5828 / 33742	FlyBaseID:	FBgn0031682	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_001107811.1	Gene:	Pank1 / 75735	MGIID:	1922985	Length:	548	Species:	Mus musculus

Alignment Length:	148	Identity:	34/148 - (22%)
Similarity:	52/148 - (35%)	Gaps:	35/148 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 QELDALADED-TRWTELVRGVLAGNMFDWGAQAISNILEQDSNFGLHSALDRIEKRPWLLDNLDS 191
            :.||..|..| |...:||:.:..|:...:|.|. |.:.....|.......:.|.|.......|.:
Mouse   408 EALDMAAKGDSTNVDKLVKDIYGGDYERFGLQG-SAVASSFGNMMSKEKRESISKEDLARATLVT 471

  Fly   192 WLNRLKGEPHKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLD 256
            ..|.:......||:    |..:|.|:.|..|:|                  :|.|:.:.|...:|
Mouse   472 ITNNIGSIARMCAL----NENIDRVVFVGNFLR------------------INMVSMKLLAYAMD 514

  Fly   257 DCSRECEVLEQAWSKGQL 274
                       .||||||
Mouse   515 -----------FWSKGQL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5828	NP_001260085.1	DUF89	54..347	CDD:280170	34/148 (23%)
Pank1	NP_001107811.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..120
		Nucleolar localization signal. /evidence=ECO:0000269\|PubMed:23152917	1..8
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..167
		Nucleolar localization signal. /evidence=ECO:0000269\|PubMed:23152917	168..185
		Fumble	189..537	CDD:281610	34/148 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5146
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D865329at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100565
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R888
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750