DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5828 and Pank2

DIOPT Version :9

Sequence 1:	NP_001260085.1	Gene:	CG5828 / 33742	FlyBaseID:	FBgn0031682	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_705721.3	Gene:	Pank2 / 74450	MGIID:	1921700	Length:	456	Species:	Mus musculus

Alignment Length:	169	Identity:	32/169 - (18%)
Similarity:	57/169 - (33%)	Gaps:	52/169 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 EDTRWTELVRGVLAGNMFDWG------AQAISNILEQDSNFGLHSALDRIEKRPWLLDNLDSWLN 194
            :.|:..:|||.:..|:...:|      |.:..|::.::..       :...|.......|.:..|
Mouse   328 DSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKR-------EAASKEDLARATLITITN 385

  Fly   195 RLKGEPHKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCS 259
            .:......||:    |..::.|:.|..|:|                  :|.:....|...||
Mouse   386 NIGSIARMCAL----NENINQVVFVGNFLR------------------VNTIAMRLLAYALD--- 425

  Fly   260 RECEVLEQAWSKGQLLVYAN------GQTGPCLDMRTLP 292
                    .||||||....:      |..|..|::..:|
Mouse   426 --------YWSKGQLKALFSEHEGYFGAVGALLELLKIP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5828	NP_001260085.1	DUF89	54..347	CDD:280170	32/169 (19%)
Pank2	NP_705721.3	Fumble	100..448	CDD:397611	29/159 (18%)
Pank2	NP_705721.3	Nuclear export signal. /evidence=ECO:0000250\|UniProtKB:Q9BZ23	154..161
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5146
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100565
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R888
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740