DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5828 and pnk-4

DIOPT Version :9

Sequence 1:	NP_001260085.1	Gene:	CG5828 / 33742	FlyBaseID:	FBgn0031682	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_508866.1	Gene:	pnk-4 / 180779	WormBaseID:	WBGene00006862	Length:	755	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	140/357 - (39%)
Similarity:	210/357 - (58%)	Gaps:	28/357 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QPDTLDLNTDGKAADYWFNCFRDMVAKFAKVAAKSQE-----EDHTATQRAEQFQAAYLQRLE-- 71
            :|||:|.|.|.:|.::|.......:....|.|..|||     ||  .|.|||.||:.:::.::
Worm   406 KPDTIDFNKDEEARNFWIEILDKTINDITKFAIASQENCSNKED--LTNRAEDFQSDFVKTMDII 468

  Fly    72 -EHQRNVPVNKGKVILGTS---ELLKLNETLLRRYGFTDPWLRQKRLENASAVARLKQRLQELDA 132
             ||.         |..|.|   .:|::.|.:|:..||.|.::::|..||.:|:|.|.:.|.::|.
Worm   469 KEHH---------VAYGNSNARNMLEVREQILQEKGFDDIYVQKKHAENCTAIAELPRVLAKIDE 524

  Fly   133 L---ADEDTRWTELVRGVLAGNMFDWGAQAISNILEQDSNFGLHSALDRIEKRPWLLDNLDSWLN 194
            |   .||.|....:.||:||||:|||||:.:..::..:|.....:|:|.:|.||||.|..||:..
Worm   525 LKNTGDEKTVLEYVSRGLLAGNVFDWGAKEVVKMMNSESGLTFQTAIDHVENRPWLFDGFDSFYK 589

  Fly   195 RLKGEPHKCAVVFVDNSGVDVVLGVLPFVRGLLKRGTKVLLCANSEPALNDVTSEELKSLLDDCS 259
              |.:.:|..::||||||.|.:||::||.|.||:.|::|::|||:.|||||:|..|:..|..:..
Worm   590 --KHKEYKSVLIFVDNSGFDYILGIIPFARELLRNGSRVIICANTSPALNDLTYREMVELAPELK 652

  Fly   260 RECEVLEQAWSKGQLLVYANGQTGPCLDMRTLPKELCDAIAANETDLLVIEGMGRALHTNLNARF 324
            .....|.:.....|::....||..||:|.|.:.::|.:.:....|||:||||||||||||.|.:|
Worm   653 NADSDLAKFIDSNQMMFVQTGQESPCMDARRVHQDLNETVKKFNTDLVVIEGMGRALHTNFNVQF 717

  Fly   325 GCETLKLAVIKNKWLAKYLGGEDMFAVVCKFE 356
            .|::||.||||.:|||..|||: ||:||.|.|
Worm   718 KCDSLKAAVIKTQWLADRLGGK-MFSVVFKHE 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5828	NP_001260085.1	DUF89	54..347	CDD:280170	119/301 (40%)
pnk-4	NP_508866.1	Fumble	23..345	CDD:281610
pnk-4	NP_508866.1	DUF89	422..739	CDD:301611	126/329 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	228	1.000	Domainoid score	I1413
eggNOG	1	0.900	-	-		E1_COG5146
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41235
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D865329at2759
OrthoFinder	1	1.000	-	-		FOG0006555
OrthoInspector	1	1.000	-	-		oto17864
orthoMCL	1	0.900	-	-		OOG6_100565
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R888
SonicParanoid	1	1.000	-	-		X3690
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710