DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn11 and stambpa

DIOPT Version :9

Sequence 1:	NP_608905.1	Gene:	Rpn11 / 33738	FlyBaseID:	FBgn0028694	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_956792.1	Gene:	stambpa / 797422	ZFINID:	ZDB-GENE-040426-1551	Length:	418	Species:	Danio rerio

Alignment Length:	200	Identity:	47/200 - (23%)
Similarity:	87/200 - (43%)	Gaps:	33/200 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DRLLRLGGAMPQAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGV--PMEVMGLMLGEFVDD-Y 63
            ||.|:  .::|.:|  ..:.:|:...|:::.:....:.||......  .:|..|::.|:.:.: :
Zfish   228 DRSLK--PSVPVSA--GHSALVNGLRQLFVPAELCQRFLKLAETNTARAVETCGILCGKLMKNAF 288

  Fly    64 TVQVIDVFAMPQTGTG---VSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDI 125
            ||..:.|   |:...|   ...|..:.:|       |.|.....:.:||.|:||....:||.||:
Zfish   289 TVTHVIV---PKQCGGPDYCDTENEEELF-------LIQDQNDLITLGWIHTHPTQTAFLSSVDL 343

  Fly   126 NTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLG---HLQKPSV 187
            :|..|::.:...::|:|..|..:..|     .|||.:..|..:|     |....|   |.:.|.:
Zfish   344 HTHCSYQMMLPESIAIVCSPKFNETG-----YFRLTDYGMDDVG-----TCKQRGFHPHPKDPPL 398

  Fly   188 QALIH 192
            .|..|
Zfish   399 FAASH 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	41/182 (23%)
stambpa	NP_956792.1	USP8_dimer	13..114	CDD:286108
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	199..218
		MPN_AMSH_like	248..418	CDD:163697	40/175 (23%)
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	329..342		5/12 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810