Protein Alignment Rpn11 and BRCC3

DIOPT Version :9

• Sequence 1: NP_608905.1
• Gene: Rpn11 / 33738
• FlyBaseID: FBgn0028694
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_005274808.1
• Gene: BRCC3 / 79184
• HGNCID: 24185
• Length: 317
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 64/228 - (28%)
• Similarity: 89/228 - (39%)
• Gaps: 65/228 - (28%)

  Fly    22 VVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTGTGVSVEAVD 86
            ||...:.|::.|.|.|..|.|..:....|||||.:||..|| |.:....||...|......|.||
Human     5 VVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDD-TSRSDSKFAYTGTEMRTVAEKVD 68

  Fly    87 PV--------------------------------FQAKMLDMLKQTGRPEMVVGWYHSHPGFGCW 119
            .|                                .:|:.|..|  ||||..|||||||||....|
Human    69 AVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAEL--TGRPMRVVGWYHSHPHITVW 131

  Fly   120 LSGVDINTQQSFEALSERAVAVV----VDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLG 180
            .|.||:.||..::.:.:..|.::    ::...:..|:|:...|:.|
Human   132 PSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSI------------------- 177

  Fly   181 HLQKPSVQALIHGLNRHYYS----ISINYRKNE 209
            ..||.|..  :|| .|.::|    |||..:|.|
Human   178 QAQKSSES--LHG-PRDFWSSSQHISIEGQKEE 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	64/228 (28%)
BRCC3	XP_005274808.1	MPN_BRCC36	13..293	CDD:163699	61/220 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810