DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn11 and stambpb

DIOPT Version :9

Sequence 1:	NP_608905.1	Gene:	Rpn11 / 33738	FlyBaseID:	FBgn0028694	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001032659.1	Gene:	stambpb / 641572	ZFINID:	ZDB-GENE-051127-31	Length:	418	Species:	Danio rerio

Alignment Length:	260	Identity:	56/260 - (21%)
Similarity:	88/260 - (33%)	Gaps:	88/260 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PQA-APPT-DAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMP 74
            |.| |||| |..:..:.....|..|.        :..||.|:.|..| ...::.|::.::.
Zfish   224 PSAPAPPTFDRSLKPSHLTTLIDGLR--------QIAVPAELCGKFL-RLANNNTIRAVET---- 275

  Fly    75 QTGTGVSVEAVD-PVFQAKMLDMLKQTGRPE-------------------MVVGWYHSHPGFGCW 119
               .|:....:: ..|....:.:.||.|.|:                   :.:||.|:||....:
Zfish   276 ---CGILCGTLNRNAFTVTHVVVPKQCGGPDYCDTENEEELFLVQDQYNLITLGWIHTHPTQTAF 337

  Fly   120 LSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQK 184
            ||.||::|..|::.:...::|:|..|..:..|     .|||.:     .|.|...|.:..|....
Zfish   338 LSSVDLHTHCSYQMMLPESIAIVCSPKFNQTG-----YFRLTD-----YGMEEISTCAQKGFHPH 392

  Fly   185 PSVQALIHGLNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDL 249
            |....|..|                                       ..|..|.||||: ||||
Zfish   393 PKDPPLFTG---------------------------------------GSHIIITEDTVS-MLDL 417

Fly 250 249
Zfish 418 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	50/251 (20%)
stambpb	NP_001032659.1	USP8_dimer	13..116	CDD:286108
stambpb	NP_001032659.1	MPN_AMSH_like	248..418	CDD:163697	48/236 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810