DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpn11 and rpn11

DIOPT Version :9

Sequence 1:	NP_608905.1	Gene:	Rpn11 / 33738	FlyBaseID:	FBgn0028694	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_594014.1	Gene:	rpn11 / 2543040	PomBaseID:	SPAC31G5.13	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	307	Identity:	208/307 - (67%)
Similarity:	248/307 - (80%)	Gaps:	2/307 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDRLLRLGGAMPQAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV 65
            :.|||:  ||........|.|:||.:|.||||||||||||:|||.|.|||||||||||||||:||
pombe     4 LQRLLQ--GARMGTGMMGDQPLVDNSECVYISSLALLKMLRHGRHGTPMEVMGLMLGEFVDDFTV 66

  Fly    66 QVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQS 130
            :|:|||||||:||||||||||||||..|:|||||||||||||||||||||||||||.||||||||
pombe    67 RVVDVFAMPQSGTGVSVEAVDPVFQKNMMDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDINTQQS 131

  Fly   131 FEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHGLN 195
            ||.|:.|||||||||||||||||||||||||||:.|::|||||||||||||:.|||:|||||||.
pombe   132 FEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPSTLMMGQEPRQTTSNLGHINKPSIQALIHGLG 196

  Fly   196 RHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLEDE 260
            |||||:.|||:|.|||:.|||||||:.|..||.|.::|.....|..::.:|..|::.|.:.:::|
pombe   197 RHYYSLRINYKKTELEEIMLLNLHKQPWAHGLLLENFNSAAEKNHASIDKMKSLSEQYTERVQNE 261

  Fly   261 EKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVF 307
            ..::||||.|:.|||||||:||:.:|.|.:.|||...|..|||::.|
pombe   262 VTLSPEQLRIQYVGKQDPKKHLDAEVQKCIDNNISSMLACMLDSVAF 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	193/264 (73%)
rpn11	NP_594014.1	MPN_RPN11_CSN5	20..285	CDD:163700	193/264 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	201	1.000	Domainoid score	I653
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4240
Inparanoid	1	1.050	423	1.000	Inparanoid score	I337
OMA	1	1.010	-	-		QHG53757
OrthoFinder	1	1.000	-	-		FOG0004641
OrthoInspector	1	1.000	-	-		oto101701
orthoMCL	1	0.900	-	-		OOG6_101835
Panther	1	1.100	-	-	LDO	PTHR10410
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1200
SonicParanoid	1	1.000	-	-		X3258
TreeFam	1	0.960	-	-
	14	13.860