Protein Alignment Rpn11 and PSMD14

DIOPT Version :9

• Sequence 1: NP_608905.1
• Gene: Rpn11 / 33738
• FlyBaseID: FBgn0028694
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_005796.1
• Gene: PSMD14 / 10213
• HGNCID: 16889
• Length: 310
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 274/310 - (88%)
• Similarity: 289/310 - (93%)
• Gaps: 2/310 - (0%)

  Fly     1 MDRLLRLGGAMP--QAAPPTDAPVVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDY 63
            |||||||||.||  ...||||||.|||||||||||||||||||||||||||||||||||||||||
Human     1 MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDY 65

  Fly    64 TVQVIDVFAMPQTGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQ 128
            ||:|||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    66 TVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQ 130

  Fly   129 QSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINPNMLVLGQEPRQTTSNLGHLQKPSVQALIHG 193
            ||||||||||||||||||||||||||||||||||.||:|||.||||||||||||.|||:||||||
Human   131 QSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHG 195

  Fly   194 LNRHYYSISINYRKNELEQKMLLNLHKKSWKDGLTLSDYNEHCSINEDTVAEMLDLAKNYNKSLE 258
            ||||||||:|||||||||||||||||||||.:||||.||:|||..||..|.|||:|||||||::|
Human   196 LNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVE 260

  Fly   259 DEEKMTPEQLAIKNVGKQDPKRHLEEKVDKVMQNNIVQCLGAMLDTIVFK 308
            :|:|||||||||||||||||||||||.||.:|.:||||||.|||||:|||
Human   261 EEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	241/264 (91%)
PSMD14	NP_005796.1	MPN_RPN11_CSN5	21..286	CDD:163700	241/264 (91%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	113..126		12/12 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147810
Domainoid	1	1.000	224	1.000	Domainoid score	I2575
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4240
Inparanoid	1	1.050	553	1.000	Inparanoid score	I1122
Isobase	1	0.950	-	0.802101	Normalized mean entropy	S108
OMA	1	1.010	-	-		QHG53757
OrthoDB	1	1.010	-	-		D1031881at2759
OrthoFinder	1	1.000	-	-		FOG0004641
OrthoInspector	1	1.000	-	-		oto90831
orthoMCL	1	0.900	-	-		OOG6_101835
Panther	1	1.100	-	-	LDO	PTHR10410
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1200
SonicParanoid	1	1.000	-	-		X3258
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750