DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn11 and mysm1

DIOPT Version :9

Sequence 1:	NP_608905.1	Gene:	Rpn11 / 33738	FlyBaseID:	FBgn0028694	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	XP_012817008.2	Gene:	mysm1 / 100126685	XenbaseID:	XB-GENE-1032957	Length:	860	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	59/244 - (24%)
Similarity:	99/244 - (40%)	Gaps:	54/244 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMP---QTGTGVSVEAVDPVF 89
            ||.::..|:|.:..|....: .||:||:.|.:.:  :..|:::.|..   ...||:..| :|||.
Frog   584 QVKVTCEAMLILDLHAHVSM-AEVIGLLGGRYTE--SESVVEICAAEPCNSLSTGLQCE-MDPVS 644

  Fly    90 QAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVV 154
            |.:..:.|...|  ..|:|||||||.|....|..||:||..::....|..|..:.        ::
Frog   645 QTQASEALASRG--YSVIGWYHSHPAFDPNPSIRDIDTQAKYQNYFSRGGAKFLG--------MI 699

  Fly   155 IDAFRLINPNMLVLGQEPRQTTSNL---GHLQKPSVQALIHGLNRHYYSISINYRKNELEQKMLL 216
            |..:...||:       |:...|.|   ..|.|       .|..|..|...:.|.:.||:.:::
Frog   700 ISPYNQRNPH-------PQSQVSCLIISDELSK-------DGSYRIPYKFDVEYMQGELQWELV- 749

  Fly   217 NLHKKSWKDGLTLSDY-NEHCSINEDTVAEMLDLAKNYNKSLEDEEKMT 264
             ..|..|    .:..| :.|.|:             :.||....:.::|
Frog   750 -FEKTRW----IIEKYKSSHSSV-------------SMNKRFRHDSELT 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn11	NP_608905.1	MPN_RPN11_CSN5	19..284	CDD:163700	59/244 (24%)
mysm1	XP_012817008.2	Myb_DNA-binding	122..166	CDD:395191
		SWIRM	391..470	CDD:398234
		MPN_2A_DUB	579..761	CDD:163698	53/210 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910