Protein Alignment Col4a1 and col-135

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001255859.1
• Gene: col-135 / 3565413
• WormBaseID: WBGene00000708
• Length: 660
• Species: Caenorhabditis elegans
• Alignment Length: 922
• Identity: 329/922 - (35%)
• Similarity: 392/922 - (42%)
• Gaps: 326/922 - (35%)

  Fly   589 IPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLK 653
            :||..|..||||..  .|:.|..|.||:.|.||:||:         ||:               |
 Worm    59 LPGPPGPPGPPGTG--TGKDGVPGTNGKDGTPGDKGD---------TGD---------------K 97

  Fly   654 GDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQ 718
            ||||..||||.                            |:.|.||..|.||..|:||..|.||.
 Worm    98 GDKGDTGAPGV----------------------------GVKGDPGAQGPPGEKGKDGDKGAPGA 134

  Fly   719 SIKGEPGFHGRDGAKGDKGSFGRSGEKGEPGSCALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPG 783
            .     |..|.||.||||||.|..||||.||.          ||:|||.|:.|..|.||..|..|
 Worm   135 K-----GSKGDDGKKGDKGSSGEKGEKGSPGQ----------KGDKGEKGEKGSNGSPGSKGDKG 184

  Fly   784 ERGYTGLKGNTGPQGPPGVEGPRGLN---GPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPR 845
            |:   |..||.||:|..|.:|.:|.:   |.:|:||:.||.|..||||..|..|..|..|..|.:
 Worm   185 EK---GADGNPGPKGDKGADGAKGADGTPGSKGDKGSDGAKGADGNPGSKGDTGDKGEKGSDGAK 246

  Fly   846 GEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGDRGDAGLPGVSGRPGIVGEK 910
            |:           .|.||..|.|||:|..|..|..||||:   ||.:||.|..|..|..|..|:|
 Worm   247 GD-----------KGANGTPGSKGDKGEKGADGAKGADGT---PGSKGDKGADGAKGADGTPGQK 297

  Fly   911 GDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGAPGNDGPKGFAGVTGA 975
            ||                  .|.:|.||.||:.|:.|..|..|:|||:||   ||.|   |..|.
 Worm   298 GD------------------KGEKGLDGPKGDKGADGTPGAKGDKGDKGA---DGAK---GADGT 338

  Fly   976 PGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPG 1040
            ||.:|..|..|:.|.||||||      ||..|..|.|||      |||:|..|..|.:|.||.||
 Worm   339 PGSKGDKGEKGLDGPKGDKGA------DGAKGANGTPGA------KGDKGEKGTDGAKGADGTPG 391

  Fly  1041 EKGNQGFPGLDGPPGLPGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPG 1105
            .||::|..|||||                     :||.|..||||..|:|
 Worm   392 AKGDKGEKGLDGP---------------------KGDKGADGTPGAKGDK--------------- 420

  Fly  1106 EKGDQGRSGIDGRDGINGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGLPGAAGAPGAVGYP 1170
                                            ||||:.||.|..|.||..|..||.||.||.|.|
 Worm   421 --------------------------------GEKGADGAKGADGTPGSKGDKGADGAKGADGTP 453

  Fly  1171 GDRGDKGEPGLSGLPGLKGETGPVGLQGFTGAPGPKGERGIRGQPGLPATVPDIRGDKGSQGERG 1235
            |.:|||||.||.                     ||||::|..|.||       .:|||
 Worm   454 GQKGDKGEKGLD---------------------GPKGDKGADGTPG-------AKGDK------- 483

  Fly  1236 YTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKGDIGPRGEIGYPGVTIKGEKG 1300
              ||||..|.:|..|..|..|.|||:||.||.|..|.:|.||:|||.|.:|:||.|
 Worm   484 --GEKGADGAKGADGTPGSKGDKGDKGLDGPKGDKGADGTPGSKGDKGEKGDIGQP--------- 537

  Fly  1301 LPGRPGRNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKGERGLAGSPGQPGQDGFP 1365
                                                     |..|.|||:|..|.|||.||||.|
 Worm   538 -----------------------------------------GQKGDKGEKGQDGQPGQKGQDGQP 561

  Fly  1366 GAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGN---DGP 1427
                                    ||||||||:| ||..|..|..||||..|.||..|:   .|.
 Worm   562 ------------------------GQKGDKGDKG-QGEKGQDGQPGQKGQDGQPGQKGDKGEKGD 601

  Fly  1428 VGAPGERGFTGPKGRDGRDGTPGLPGQKGEPGMLPPPGPKGEPGQPGRNGPKGEPGRPGERGLIG 1492
            :|.||::|..|.||:||:      |||||:.|.   ||.||:.||||:.|.|||.|.
 Worm   602 IGQPGQKGDKGDKGQDGQ------PGQKGQDGQ---PGQKGQDGQPGQKGDKGEKGE-------- 649

  Fly  1493 IQGERGEKGERG 1504
             :||:||||::|
 Worm   650 -KGEKGEKGQKG 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478
		gly_rich_SclB	<355..>642	CDD:468478	19/52 (37%)
		gly_rich_SclB	<543..820	CDD:468478	84/233 (36%)
		gly_rich_SclB	<727..>968	CDD:468478	98/243 (40%)
		gly_rich_SclB	<969..>1218	CDD:468478	84/248 (34%)
		gly_rich_SclB	<1186..>1420	CDD:468478	73/233 (31%)
		gly_rich_SclB	<1321..>1547	CDD:468478	72/187 (39%)
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
col-135	NP_001255859.1	gly_rich_SclB	<66..>256	CDD:468478	97/272 (36%)
		gly_rich_SclB	<184..>409	CDD:468478	114/298 (38%)
		gly_rich_SclB	<343..>567	CDD:468478	131/414 (32%)
		Collagen	582..638	CDD:460189	29/64 (45%)