Protein Alignment Col4a1 and Col10a1

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_037272.1
• Gene: Col10a1 / 25681
• RGDID: 2371
• Length: 680
• Species: Rattus norvegicus
• Alignment Length: 677
• Identity: 264/677 - (38%)
• Similarity: 308/677 - (45%)
• Gaps: 192/677 - (28%)

  Fly   382 GKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPG 446
            |:.|:.|||| |.|.||.|||.||.|..|| |:|   ||.|..|||||.|.:. .|..||||:||
  Rat    57 GEQGIPGPPG-PAGPRGHPGPSGPPGKPGY-GSP---GLQGEPGLPGPPGISA-TGKPGLPGKPG 115

  Fly   447 NEGPPGKKGEKGTAGLNGPKGSIGPIGHPGP-----PGPEGQKGDAGLPGYGIQGSKGDAGIPGY 506
            ..||.|.||:.|.|||.||:|..||.|.|||     ||..||:|..|.|  |.:|..|:.|.||.
  Rat   116 ERGPHGHKGDIGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGLTGAP--GSRGFPGEKGAPGA 178

  Fly   507 PGLKGSKGERGFKGNAGAPGDSKLGRPGTPGAAGAPGQKGDAGRPGTPGQKGDMGIKGDVGGKCS 571
            ||:.|.|||.|:            |.||.||..|.||.:|..|.||:||
  Rat   179 PGVNGQKGETGY------------GTPGRPGERGLPGPQGPVGPPGSPG---------------- 215

  Fly   572 SCRAGPKGDKGTSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATG 636
               .|.:|:.|..|.|||         .|:||:|||.|..|..|..||||::|.:| .|.|||||
  Rat   216 ---VGRRGENGFPGQPGI---------KGDRGFPGEAGPPGPPGPQGPPGKQGREG-IGKPGATG 267

  Fly   637 EPGKPALCDLSLIEPLKGDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGND 701
            .||:|.         :.|:||:|||               |||.||.|..||
  Rat   268 SPGRPG---------IPGEKGHPGA---------------PGIAGPPGAPGF------------- 295

  Fly   702 GTPGRAGRDGYPGIPGQSIKGEPGFHGRDGAKGDKGSFGRSGEKGEPGSCALDEIKMPAKGNKGE 766
                  |:.|.||:.||  :|..|..|..||||::|                     || |:.||
  Rat   296 ------GKQGLPGLRGQ--RGPAGLPGAPGAKGEQG---------------------PA-GHPGE 330

  Fly   767 PGQTGMP---GPPGEDGSPGERGYTGLKGNTGPQGPPGVEGPRGLNGPRGEKGNQGAVGVPGNPG 828
            ||.||.|   ||.|..|.||..|..|.||.||..||.|..|.||..||               ||
  Rat   331 PGLTGSPGNMGPQGPKGIPGNHGIPGTKGETGLVGPAGPPGARGARGP---------------PG 380

  Fly   829 KDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPGADGSVGYPGDRG 893
            .||..|.||..|..||:|.||:  |||.|.||:.|..|.:|..|||||.|.||.:|..   |.||
  Rat   381 LDGKTGYPGDPGLNGPKGNPGL--PGPKGDPGVGGAPGLRGLVGPTGPKGVPGHNGEA---GPRG 440

  Fly   894 DAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDR 958
            :.|:||..            |||      ||||:|                     |.||:|||.
  Rat   441 EPGIPGTR------------GPI------GPPGIP---------------------GFPGSKGDP 466

  Fly   959 GAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGD 1023
            |.||..||.|..    ..|..||||.||..|.:|..|..||.|..||   .||||.|....|  .
  Rat   467 GKPGAPGPAGIV----TKGLNGPAGPPGRPGPRGHTGEPGLPGPPGP---PGPPGPPSQAVI--P 522

  Fly  1024 QGLAGAPGQQGLDGMPGEKGNQGFPGL 1050
            .|...:..:..|.|||....|||..|:
  Rat   523 DGFTKSGQRPRLSGMPLVSANQGVTGM 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478
		gly_rich_SclB	<355..>642	CDD:468478	118/264 (45%)
		gly_rich_SclB	<543..820	CDD:468478	96/279 (34%)
		gly_rich_SclB	<727..>968	CDD:468478	92/243 (38%)
		gly_rich_SclB	<969..>1218	CDD:468478	30/82 (37%)
		gly_rich_SclB	<1186..>1420	CDD:468478
		gly_rich_SclB	<1321..>1547	CDD:468478
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
Col10a1	NP_037272.1	None