Protein Alignment Col4a1 and col-173

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_509162.1
• Gene: col-173 / 180960
• WormBaseID: WBGene00000746
• Length: 325
• Species: Caenorhabditis elegans
• Alignment Length: 273
• Identity: 91/273 - (33%)
• Similarity: 111/273 - (40%)
• Gaps: 92/273 - (33%)

  Fly   597 GPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPA-------LCDLSLIEPLKG 654
            |.|||.|.||:.||||::|:               ||:.|.||...       :.|....|.|..
 Worm   135 GSPGEPGSPGQDGHDGVDGR---------------PGSDGNPGADMHLDDTYNMADQFCFECLPA 184

  Fly   655 DKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQS 719
            ..|.||.||.|         |:|||||.:||               |..|||.|..|..|.||.
 Worm   185 PTGPPGPPGLK---------GMPGIPGNQGE---------------DAGPGRQGMPGPTGPPGP- 224

  Fly   720 IKGEPGFHGRDGAKGDKGSFGRSGEKGEPGSCALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPGE 784
             :|.|               |.:|::||.|.   |.|.|.   .|..||..|.|||.|.|
 Worm   225 -RGPP---------------GETGDEGEGGP---DGIPME---KKSPPGPRGPPGPAGPD----- 262

  Fly   785 RGYTGLKGNTGPQGPPGVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPG 849
                      |||||.|..|.:|..||.|::|.:|.:|.||.||:      ||::|..|.||..|
 Worm   263 ----------GPQGPEGRSGKQGPPGPTGQEGEEGVIGEPGKPGE------PGKSGAAGARGPAG 311

  Fly   850 ISR--PGPMGPPG 860
            ...  |.|...||
 Worm   312 PCNHCPNPRTAPG 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478
		gly_rich_SclB	<355..>642	CDD:468478	17/44 (39%)
		gly_rich_SclB	<543..820	CDD:468478	74/229 (32%)
		gly_rich_SclB	<727..>968	CDD:468478	46/136 (34%)
		gly_rich_SclB	<969..>1218	CDD:468478
		gly_rich_SclB	<1186..>1420	CDD:468478
		gly_rich_SclB	<1321..>1547	CDD:468478
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
col-173	NP_509162.1	Col_cuticle_N	22..72	CDD:198156
		Collagen	<135..>163	CDD:460189	16/42 (38%)