Protein Alignment Col4a1 and col-88

DIOPT Version :10

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_497131.1
• Gene: col-88 / 175170
• WormBaseID: WBGene00000663
• Length: 302
• Species: Caenorhabditis elegans
• Alignment Length: 278
• Identity: 102/278 - (36%)
• Similarity: 118/278 - (42%)
• Gaps: 82/278 - (29%)

  Fly   390 PGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGKK 454
            |.|.....|.||||         ||||..||:|.:|..||   ||| .|||       :|...:.
 Worm    89 PQPSNCPAGPPGPP---------GAPGDAGLDGENGQAGP---NGQ-DGAG-------QGSSQQP 133

  Fly   455 GEKGTAGLNGPKGSIGPIGHPGPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFK 519
            .|..|.          |.|.|||.||:   |.||.|     |:.|.||.||.||..|..|..|.:
 Worm   134 SECITC----------PAGAPGPQGPD---GPAGAP-----GADGQAGSPGAPGQDGQPGGPGAQ 180

  Fly   520 GNAGAPGDSKLGRPGTPGAAGAPGQKGDAGR--PGTPGQKGDMGIKGDVGGKCSSCRAGPKGDKG 582
            |:|||||:.     ||||..|||||.|..|.  .|.|                     ||:|..|
 Worm   181 GDAGAPGND-----GTPGQDGAPGQNGQRGNGAAGAP---------------------GPQGPAG 219

  Fly   583 TSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPA-LCDL 646
            .:|..|.||.|         |.||.:|..||.|..|.||:.||||..|..|..||||..| .|..
 Worm   220 NAGQAGQPGAD---------GQPGAQGSAGIAGAPGQPGKAGEDGEAGENGTDGEPGTDAEYCQC 275

  Fly   647 S------LIEPLKGDKGY 658
            .      .:||...::||
 Worm   276 PPRTGAIEVEPATQEEGY 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	gly_rich_SclB	<107..>361	CDD:468478
		gly_rich_SclB	<355..>642	CDD:468478	96/253 (38%)
		gly_rich_SclB	<543..820	CDD:468478	41/125 (33%)
		gly_rich_SclB	<727..>968	CDD:468478
		gly_rich_SclB	<969..>1218	CDD:468478
		gly_rich_SclB	<1186..>1420	CDD:468478
		gly_rich_SclB	<1321..>1547	CDD:468478
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
col-88	NP_497131.1	Col_cuticle_N	12..57	CDD:460226
		gly_rich_SclB	<111..>269	CDD:468478	83/221 (38%)