Protein Alignment Col4a1 and Col13a1

DIOPT Version :9

• Sequence 1: NP_723044.1
• Gene: Col4a1 / 33727
• FlyBaseID: FBgn0000299
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: XP_011241624.1
• Gene: Col13a1 / 12817
• MGIID: 1277201
• Length: 760
• Species: Mus musculus
• Alignment Length: 1011
• Identity: 342/1011 - (33%)
• Similarity: 404/1011 - (39%)
• Gaps: 355/1011 - (35%)

  Fly   198 EKGEPAKENGDYAKGEKGEPGWRGTAGLAG-----PQGFPGEKG--------------------- 236
            |:...|..:|....||.|.|| .||..||.     |.  ||..|
Mouse     4 ERTRKAAASGSRGPGELGAPG-PGTVALAEQCARLPS--PGCCGLLALALCSLALSLLAHFRTAE 65

  Fly   237 ----------ERGDSGPYGAKGPRGEHGLKG------EKGASCYGPMKPGAPGIKGEKGEPASSF 285
                      |||:.        :.|..:.|      ::....|...:..||     |..|..:.
Mouse    66 LQARVLRLEAERGEQ--------QMEKAILGRVNQLLDEKWKFYSRRRREAP-----KMSPGCNC 117

  Fly   286 PVKPTHTVMGPRGDMGQKGEPGLVGRKGEPGPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGS 350
            |..|.          |..|.|||.|.||..|..|..|:.||.||||.||..|    ....||.|.
Mouse   118 PPGPP----------GPTGRPGLPGDKGAIGMPGRVGIKGQPGEKGAPGDAG----MSIVGPRGP 168

  Fly   351 TGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAP 415
            .||.|.||.|   |.||..|..|.||..|..|:.||:||       ||.|||.|.||.:|..| .
Mouse   169 PGQPGTRGFP---GFPGPIGLDGRPGHPGPKGEMGLVGP-------RGQPGPQGQKGEKGQCG-E 222

  Fly   416 GPQG----LNGVDGLPGP----QGYNGQKGGAGLPGRPGNEGPPGKKGEKGTAGLNGPKGSIGPI 472
            .|..    ||.|...|.|    :.:.|::...|:.|.||..||||..|..|..||.||   |||.
Mouse   223 YPHRLLPLLNSVRLAPPPVIKRRTFQGEQSQTGIQGPPGPPGPPGPSGPLGHPGLPGP---IGPP 284

  Fly   473 GHPGPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSKLGRPGTPG 537
            |.||||||   |||.|:.||  .|.||:.|:||.||..|:|         |.||.:..|..|.||
Mouse   285 GLPGPPGP---KGDPGIQGY--HGRKGERGMPGMPGKHGAK---------GVPGIAVAGMKGEPG 335

  Fly   538 AAGAPGQKGDAGRPGTPGQKGDMGIKGDVGGKCSSCRAGPKGDKGTSGLPGIPGKDGARGPPGER 602
            ..|..|:||.||.||..||||:   |||.|.                   .|.|..|..||||..
Mouse   336 TPGTKGEKGAAGSPGLLGQKGE---KGDAGN-------------------AIGGGRGEPGPPGLP 378

  Fly   603 GYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKGDKGYPGAPGAKGV 667
            |.||.:|..|::||.||||:                              :||||.|||.|.:|.
Mouse   379 GPPGPKGEAGVDGQAGPPGQ------------------------------QGDKGQPGAAGEQGP 413

  Fly   668 QGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPGIPGQSIKGEPGFHGRDGA 732
            .|.|||                                               |||||
Mouse   414 SGPKGA-----------------------------------------------KGEPG------- 424

  Fly   733 KGDKGSFGRSGEKGEPGSCALDEIK-MPAKGNKGEPGQTGMPGPPGEDGSPGERGYTGLKGNTGP 796
            ||:...:  :|...|    ||.||: :...|..|.|||||.||||   |:||:||..||
Mouse   425 KGEMVDY--NGSINE----ALQEIRTLALMGPPGLPGQTGPPGPP---GTPGQRGEIGL------ 474

  Fly   797 QGPPGVEGPRGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPGISRPGPMGPPGL 861
            .||||.:|.:   ||||:.|:.|..|..|.||||   |.||..|:.||.|.|
Mouse   475 PGPPGHDGDK---GPRGKPGDMGPAGPQGPPGKD---GPPGMKGEVGPPGSP------------- 520

  Fly   862 NGLQGEKGDRGPTGPIGFPGADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPG 926
                ||||:.|..||   .|.||..|..|:.||.|.||.:|.|                  ||.|
Mouse   521 ----GEKGETGQAGP---QGLDGPTGEKGEPGDEGRPGATGLP------------------GPIG 560

  Fly   927 VPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAK 991
            :||..|.:|..|.||:||                         |.|.|.||..||.|.||:.|..
Mouse   561 LPGFTGEKGEAGEKGDPG-------------------------AEVPGPPGPEGPPGPPGLQGFP 600

  Fly   992 GDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPGL 1056
            |.||..||.|:.|..|.:|.         |||:|..|.||..||||.||.      ||..||.|:
Mouse   601 GPKGEAGLEGSKGEKGSQGE---------KGDRGPLGLPGASGLDGRPGP------PGTPGPIGV 650

  Fly  1057 PGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPGEKGDQGRSGIDGRDGI 1121
            ||.|..||::|..|..|:.|.||.||.||           :|   ||||:||::|..      |.
Mouse   651 PGPAGPKGERGSKGDPGMTGPTGAAGLPG-----------LH---GPPGDKGNRGHR------GF 695

  Fly  1122 NGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGL 1157
            .|||||                     ||.||:|||
Mouse   696 KGEKGE---------------------PGLPGLDGL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Col4a1	NP_723044.1	Collagen	104..161	CDD:189968
		Collagen	322..380	CDD:189968	26/57 (46%)
		Collagen	413..465	CDD:189968	20/59 (34%)
		Collagen	499..561	CDD:189968	27/61 (44%)
		Collagen	574..632	CDD:189968	18/57 (32%)
		Collagen	657..714	CDD:189968	10/56 (18%)
		Collagen	765..824	CDD:189968	29/58 (50%)
		Collagen	854..911	CDD:189968	19/56 (34%)
		Collagen	884..943	CDD:189968	20/58 (34%)
		Collagen	923..982	CDD:189968	18/58 (31%)
		Collagen	1028..1085	CDD:189968	27/56 (48%)
		Collagen	1229..1287	CDD:189968
		Collagen	1318..1376	CDD:189968
		Collagen	1399..1458	CDD:189968
		Collagen	1477..1534	CDD:189968
		C4	1555..1662	CDD:128421
		C4	1663..1777	CDD:128421
Col13a1	XP_011241624.1	Collagen	147..220	CDD:189968	40/86 (47%)
		Collagen	515..573	CDD:189968	30/95 (32%)
		Collagen	658..709	CDD:189968	29/91 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910