DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vkg and Col4a4

DIOPT Version :9

Sequence 1:	NP_001260071.1	Gene:	vkg / 33726	FlyBaseID:	FBgn0016075	Length:	1940	Species:	Drosophila melanogaster
Sequence 2:	NP_001008333.1	Gene:	Col4a4 / 301562	RGDID:	1305355	Length:	159	Species:	Rattus norvegicus

Alignment Length:	133	Identity:	61/133 - (45%)
Similarity:	73/133 - (54%)	Gaps:	18/133 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GKIC---NTTLCDCKGIKGRMGAPGPIGVPGLEGPAGDIGPPGRAGPLGEKGDVGEYGEQGEKGH 91
            |..|   |.::|.|...||..|.|||:|.   :||.|.:||||..|..||||..|:.|..|..|.
  Rat    36 GSPCGGRNCSVCQCFPEKGSRGHPGPLGP---QGPIGPLGPPGPIGIPGEKGLRGDSGLPGPPGE 97

  Fly    92 RGDIGPKGEMGYPGIMGKSGEPGTPGPRGIDGCDGRPGMQGPSGAPGQNGVRGPPGKPGQQGPPG 156
            :||.||.|..|:||:.|..|.||.||||      |:|||.      |.||.||.||.||::|.||
  Rat    98 KGDKGPTGVPGFPGVDGVPGHPGPPGPR------GKPGMD------GYNGSRGDPGYPGERGAPG 150

  Fly   157 EAG 159
            ..|
  Rat   151 PGG 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vkg	NP_001260071.1	Collagen	60..119	CDD:189968	30/58 (52%)
		Collagen	102..152	CDD:189968	24/49 (49%)
		Collagen	277..334	CDD:189968
		Collagen	534..593	CDD:189968
		Collagen	814..871	CDD:189968
		Collagen	957..1014	CDD:189968
		Collagen	990..1049	CDD:189968
		Collagen	1070..1128	CDD:189968
		C4	1515..1624	CDD:128421
		C4	1625..1737	CDD:128421
Col4a4	NP_001008333.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BAFZ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000443
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24023
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910