Protein Alignment Rtnl1 and rtn4b

DIOPT Version :9

• Sequence 1: NP_001162875.1
• Gene: Rtnl1 / 33721
• FlyBaseID: FBgn0053113
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001035425.1
• Gene: rtn4b / 678586
• ZFINID: ZDB-GENE-030710-2
• Length: 875
• Species: Danio rerio
• Alignment Length: 661
• Identity: 169/661 - (25%)
• Similarity: 266/661 - (40%)
• Gaps: 192/661 - (29%)

  Fly   109 GISGLT----TDFMNAER-GFSAPLAPFSETVAQAPVIP--AQAPAVPDHAPAVPAP-----VAP 161
            |::.::    |:..:||: .....|...||.|.:...:|  :..|..|.|.||..||     :||
Zfish   236 GVTSVSPEPITEITSAEQTSEETSLTQISEDVTEETSVPPVSGPPPPPPHHPAAAAPPPDRSLAP 300

  Fly   162 APAVPAPLPVEE-----------------------DLLGSFTDQPSAPLQAF--QPTAPSTANFY 201
            ..|.| |.|..|                       :...|........:.||  :|:|.|..:..
Zfish   301 CNARP-PEPCGEPHSELPPAGEPEVSVSVFQTLPSERCRSLVSSAGLAMDAFGREPSATSDPDLL 364

  Fly   202 DDEEDDFLGKPTTAAPAAPVAPLTKANQDSDTESP----------------SVSYTPSPAKKPIV 250
            ...:||.:.:..::      |.|.::...||:.||                |.:..|:|.::|:
Zfish   365 SPSDDDLMLEMKSS------AGLEESRSVSDSPSPDLLQDAYEDLQTPGALSAAEPPNPEQRPV- 422

  Fly   251 DALKDQDNEKFISSEDLASDFKE-EPRSAPTPAPAPAPILDAAPAVAPAPVAVPVSVPVAKPQPV 314
             ||.|......::.|.|.|...| .|..:|....:|.|.|.||.:            |.::...:
Zfish   423 -ALPDILQSSPLNPEKLDSGSSEGSPDCSPAHRCSPNPPLSAAGS------------PDSRILLL 474

  Fly   315 PVAVPVTTALITDLDDEEV-----------VFKPTVQEAPKAPTI-----AAPV-VEPKPEPPK- 361
            ...|..|.|...:...::|           :.|...||:.:..|:     .||. .:..|.||:
Zfish   475 REMVEETEARAVEKVQQDVQQEVQQEAQAQLEKQVQQESQQGCTVLDLLQEAPAHTQTLPPPPQQ 539

  Fly   362 -----------------PKVE-----PAKPKVVPV-------------------APVESTQP--- 382
                             |.||     |:.....||                   |..|..:|
Zfish   540 QTDAPAELLQGLQFSSGPHVELWDSSPSADSFSPVLDAEQQKHSENTHSHTHIDAADEEQEPSSS 604

  Fly   383 -------QPKIASVEE-IFCKYGL--------DAWFKPER-------LHP--------------- 409
                   :|...:.|| :..:.||        :|...||:       |.|
Zfish   605 EEFEFVERPAAGAAEEFVELQDGLTSITAPPPEAAEAPEQKQSSTCLLSPAEGGGPADGEERSDV 669

  Fly   410 -----------------QVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGT 457
                             .|..|:|||||:.|.:|.|:.|:.|..:|..|||||.:|.:|..|..|
Zfish   670 QQTCPAGHTAGAPADPTAVLQLLYWRDVRASALVLGSLLLLLLFLSCCSVISVLSYSALCLLTLT 734

  Fly   458 VAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDII 522
            ::.|::.:|.||::||.:||||:.|||.|:.||.:.|...:...:..||..:.||||||||||::
Zfish   735 LSTRVFTAVLQAMRKTEDGHPFRQYLERDVLLSADAVHTHSEALLRRINTALVELRRLFLVEDLV 799

  Fly   523 DSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIR 587
            ||:|..|.||:.||||:||||:||:|:|.:..|:.|..||.::..||..:.::.:::.|...|:.
Zfish   800 DSLKLAVGLWLLTYVGSWFNGLTLLIIALIGAFSGPIAYERHQSEIDQFISMINTQMREALGKVL 864

  Fly   588 VAIPIGNKKPE 598
            ..:|.|.||.:
Zfish   865 AMVPGGKKKSD 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl1	NP_001162875.1	Reticulon	411..575	CDD:280592	75/163 (46%)
rtn4b	NP_001035425.1	Reticulon	688..852	CDD:280592	75/163 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930