Protein Alignment Rtnl1 and rtn3

DIOPT Version :9

• Sequence 1: NP_001162875.1
• Gene: Rtnl1 / 33721
• FlyBaseID: FBgn0053113
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_021333122.1
• Gene: rtn3 / 394047
• ZFINID: ZDB-GENE-030710-5
• Length: 1116
• Species: Danio rerio
• Alignment Length: 657
• Identity: 182/657 - (27%)
• Similarity: 282/657 - (42%)
• Gaps: 141/657 - (21%)

  Fly     4 NFDELK-----KEAAATNEDIFKQAQRAYEDSALGGDTGNVSGGAQDDNAHTEHYFANEQKKLDF 63
            :|:.||     ||...|:|.:|.          |..|..:.|....|...:.:||.:.|....|.
Zfish   539 SFEPLKESFLDKELDKTSEILFD----------LPPDISSPSNEPSDVETYLDHYASEELALKDQ 593

  Fly    64 GDAQEFVQRLAADAKDAKLDL----------------DTKFAQKTDDF---------------ED 97
            .::..|.:.     |..|.:|                ...|...|||.               |.
Zfish   594 LNSSCFKEN-----KVEKTELPKSVCLPGNKNICTLAQESFENVTDDINETLNEFSLDYESVPEP 653

  Fly    98 FLRDAGKEVKQGISGLTTDFMNAERGFSAP--LAPFSETVAQAPVIPAQAPAVPDHAPAVPAPVA 160
            ||.|...:....|..:..  .|....|.:.  .:....:..|...:|.|:   .|..|    ||.
Zfish   654 FLTDPSSDYPDDIETILP--QNEMPSFDSEDLKSEIKTSTLQNQELPVQS---TDQTP----PVQ 709

  Fly   161 PAPAVPAPLPVEEDLLGSFTDQPSAPLQAFQPTAPSTANFYDDEEDDFLGK--PTTAAPA----A 219
            ..|  |||.|       ||.::.|:.:.  .....|.||  .|.|...:.|  |....|.    .
Zfish   710 ENP--PAPFP-------SFHNEQSSKIS--DVITVSVAN--KDAELPVITKSEPQVMTPKDLLDR 761

  Fly   220 PVAPLTKANQDSDTESPSVSYTPSPAK--KPIVDALKDQDNEKFISSEDLASDFK---EEPRSAP 279
            |.:|  .|..|::|.....|.|.|...  :.:.:.||.:.:|:   .|.|:...|   :.|:||.
Zfish   762 PDSP--DAMSDTETLEAECSVTASTDSFMEFMRECLKSRQDEE---PETLSPGHKTIDQNPKSAE 821

  Fly   280 TPAPAPAPILDAAPAVAPAPVAVPVSVPVAKPQPVPVAVPVTTALITDL------DDEEVVFKPT 338
            ..: :||.|:|....                        .:|.:.:.:|      :||.::...|
Zfish   822 NQS-SPAMIMDLEQE------------------------RLTISALKELGSSQEEEDENIITMKT 861

  Fly   339 VQEAPKAPTIAAPVVEPKPEPPKPKVEPAKPKVVPVAPVESTQPQPKIASVEEIFCKYGLDAWFK 403
            |.:..|||.       |.|.|.....  :....:|    ...||...:....|....:..:|:..
Zfish   862 VPKLEKAPL-------PTPNPASSVT--SSSHTLP----NEYQPDSLLPKEVEAIDIWVAEAYHL 913

  Fly   404 PERL------HPQVESLIYWRDVKKSGIVFGAGLITLAAISSFSVISVFAYLSLLTLFGTVAFRI 462
            .|.:      |..|..|::|||.||||:|||..|:.|.::::||||||.:||.|..|..|::|||
Zfish   914 AEHVLTAILTHLTVNDLVHWRDPKKSGVVFGVSLLLLLSLAAFSVISVVSYLLLSLLCVTISFRI 978

  Fly   463 YKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVAHINGFISELRRLFLVEDIIDSIKF 527
            ||||.|||||:|||||||..::.|:|:..|..:......::|:|..:.::.|||||||::||:|.
Zfish   979 YKSVIQAVQKSNEGHPFKALMDKDVTVPPETFRKHVDGCLSHVNRALKQMSRLFLVEDLVDSLKL 1043

  Fly   528 GVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSIDTHLDLVRSKLTEITDKIRVAIPI 592
            .|::|:.|||||.|||:|::|||.:.||::|.:||.||..||.::|:.|::......|::..:|.
Zfish  1044 AVVMWLLTYVGAVFNGITILILADILLFSVPPIYEKNKTQIDHYIDIARTQFNTTVAKLQEKLPG 1108

  Fly   593 GNKKPEA 599
            ..|:.:|
Zfish  1109 AMKRCKA 1115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl1	NP_001162875.1	Reticulon	411..575	CDD:280592	83/163 (51%)
rtn3	XP_021333122.1	XPG_I	<416..>853	CDD:331126	77/380 (20%)
		Reticulon	927..1091	CDD:308200	83/163 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840