Protein Alignment Rtnl1 and rtn1a

DIOPT Version :9

• Sequence 1: NP_001162875.1
• Gene: Rtnl1 / 33721
• FlyBaseID: FBgn0053113
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001025138.2
• Gene: rtn1a / 323706
• ZFINID: ZDB-GENE-030131-2426
• Length: 818
• Species: Danio rerio
• Alignment Length: 680
• Identity: 189/680 - (27%)
• Similarity: 295/680 - (43%)
• Gaps: 152/680 - (22%)

  Fly    10 KEAAATNEDIFKQAQRA---YEDSALGGDTGNVSGGAQDDNAHTEHYF-----ANEQKKLDFGDA 66
            ||::....|:.:..:::   .||:.:...||:..|         :|.|     .::::..||...
Zfish   200 KESSHDPFDLGRYLEKSPLGSEDTEVKTSTGSAGG---------QHAFPYVEDPSDEEMADFRSY 255

  Fly    67 QEFVQRLAADAKDAKLDLDTKFAQKTDDFEDFLRDAGKEVKQ-----GISGLTTDFMNAERGFSA 126
            :.  ......|...|:.:.|:......:........|...:.     |..||.|..::.....||
Zfish   256 RR--METPQSASPVKITVTTESHSTASEPVRVSPQGGMSERDSVLSFGQQGLPTVTLSEPEDDSA 318

  Fly   127 PLAPFSETVAQAPVIPAQAPAVPDHAPA---VPAPVAPAPA----------------VPAPLPVE 172
                           .:.|...|:|:|.   .|:.|...||                .|.|.|:.
Zfish   319 ---------------ASSANHSPNHSPTGRESPSDVLFHPAGMKSMSSTQDSSSISSHPNPPPIH 368

  Fly   173 -------------EDLLGS-----------FTDQPSAPLQ-----------AFQPTA-----PST 197
                         :||.||           ..::..:||.           .|.||:     ||.
Zfish   369 DIKTSAKPSSPWAQDLQGSGDESGDSEIEQVAEELDSPLHDLTSKTPPAKGGFSPTSNPFEPPSY 433

  Fly   198 ANFYDDEEDDFLGKPTTAAPAAPVAPLTKANQDSDTESPSVSYTPSPAKKPIVDALKDQ-----D 257
            .:..|...:.| .||.|..        ..|:...|..:.|.......:..|:...|:::     |
Zfish   434 TSATDKASNPF-DKPQTNK--------VSASNPFDLSAGSKMGFGQSSNPPLYSLLREEREAELD 489

  Fly   258 NEKFISSEDLASDFKEEPRSAPTPAPAPAPILDAAPAVAPAPVAVPVSVPVAKPQPVPVAVPVTT 322
            ::..|.|....|..:|:..|||.|....:|::....:..|...:...|.|..:|:.|...
Zfish   490 SDLLIESASEESPKREQEYSAPKPPEPSSPLITDNMSSKPITTSSVSSSPFTEPRVVSAQ----- 549

  Fly   323 ALITDLDDEEVVFKPTVQEAPKAPTIAAPVVEPKPEP-------PKPKV---EPAKPKVVPVAPV 377
                         |...:|..|....|||:.:|||:|       |:|.|   ....|:..|....
Zfish   550 -------------KEPEKEKEKEKEKAAPIEKPKPQPEDSWSTKPRPAVMGTSTVTPEKQPSQET 601

  Fly   378 ESTQPQPKIASVEEIFCKYGLDAWFKPERLH----PQVESLIYWRDVKKSGIVFGAGLITLAAIS 438
            ||......::|..|......|       .||    .:|..|::|||:|:||:|||:.|:.|.:::
Zfish   602 ESKSKSSIVSSSTEKEADLSL-------LLHGFSRQKVVDLVHWRDLKQSGLVFGSVLLLLFSLT 659

  Fly   439 SFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQNIAGVAVA 503
            .|||:||.|||:|..|..|::||:||||.||||||:||||||.|||::::||.:::.........
Zfish   660 QFSVVSVIAYLALAVLSATISFRVYKSVLQAVQKTDEGHPFKSYLEVEISLSADQISKYVDKTQL 724

  Fly   504 HINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKVYENNKQSI 568
            :||..:.||||||||:|::|||||.|::|:.|||||.|||:||:|||.:|:|::|.|||..:..|
Zfish   725 YINTTMKELRRLFLVQDLVDSIKFAVLMWLLTYVGALFNGLTLLILAVISMFSVPVVYEKYQTQI 789

  Fly   569 DTHLDLVRSKLTEITDKIRVAIPIGNKKPE 598
            |.:|.|||:::..:..|||..:| |.||.|
Zfish   790 DQYLGLVRTQVNSVMGKIREKVP-GAKKKE 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl1	NP_001162875.1	Reticulon	411..575	CDD:280592	87/163 (53%)
rtn1a	NP_001025138.2	Reticulon	632..796	CDD:280592	87/163 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592792
Domainoid	1	1.000	192	1.000	Domainoid score	I3161
eggNOG	1	0.900	-	-		E1_KOG1792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3410
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000492
OrthoInspector	1	1.000	-	-		otm26095
orthoMCL	1	0.900	-	-		OOG6_104855
Panther	1	1.100	-	-	O	PTHR45799
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2275
SonicParanoid	1	1.000	-	-		X4350
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.780