Protein Alignment Rtnl1 and Rtn2

DIOPT Version :10

• Sequence 1: NP_001162875.1
• Gene: Rtnl1 / 33721
• FlyBaseID: FBgn0053113
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_963856.1
• Gene: Rtn2 / 308410
• RGDID: 1303245
• Length: 469
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 138/503 - (27%)
• Similarity: 224/503 - (44%)
• Gaps: 122/503 - (24%)

  Fly   186 PLQAFQPTAPSTAN-----------------------FYDDEEDDFLGKPTTAAPAAPVAPLT-- 225
            |:.|....|||||:                       |.:|||::     ||:........||
  Rat     6 PVFAHCKEAPSTASSTPDSTEGGNDDSDFRELHTAREFSEDEEEE-----TTSQDWGTPRELTFS 65

  Fly   226 ----KANQDSDTESPSVSYTPSPAKKPIVDALKDQDNEKFISSEDLASDFKEEPRSAPTPAPAPA 286
                .....|.....||...|.|..:.:                       .|||. |.|.|:..
  Rat    66 YIAFDGVVGSGGRRDSVVRRPRPQGRSV-----------------------SEPRD-PPPQPSLG 106

  Fly   287 PILDAAPAVAPAPV----AVPVSVPVAKPQPVPVAVPV-----------------------TTAL 324
            ..|::.|:::.:|.    ..|.:||       |...|:                       .|:.
  Rat   107 DSLESIPSLSQSPEPGRRGDPDTVP-------PAERPLEELRLRLDQLGWAVRSAGSGEDSATSS 164

  Fly   325 ITDLDDEEVVFKPTVQEAPKA--PTIAAPVVEP---KPEPPKPKVEPAK--PKVVPVAPVES--- 379
            .|.|::||    |...||.:|  ..:...:.:|   :.|...|::.|:.  |:....:|..|
  Rat   165 STPLENEE----PDGLEASEAGETNLELRLAQPLHLQFEGLTPQLSPSSGIPQAHTPSPQRSQDL 225

  Fly   380 ----TQPQP-------KIASVEEIFCKYGLDAWFKPE-RLHP--QVESLIYWRDVKKSGIVFGAG 430
                .:|.|       ::...|.|..:. |::..:.| .|.|  .|..|:||:|.:.||.:|...
  Rat   226 NTGPDEPLPNGEGEHWRLLEQEPITAQC-LNSTDQSEFTLEPLLLVADLLYWKDTRTSGAIFTGL 289

  Fly   431 LITLAAISSFSVISVFAYLSLLTLFGTVAFRIYKSVTQAVQKTNEGHPFKDYLELDLTLSHEKVQ 495
            :.:|..:..||::||.|:|:||.|..|::.|:|:.|.|||.:.:..:||:.||::||||:.|:.:
  Rat   290 MASLLCLLHFSIVSVAAHLALLGLCATISLRVYRKVLQAVHRGDGTNPFQAYLDMDLTLTREQTE 354

  Fly   496 NIAGVAVAHINGFISELRRLFLVEDIIDSIKFGVILWVFTYVGAWFNGMTLVILAFVSLFTLPKV 560
            .::....:|:....::||..|||||::||:|..::.::.|:|||.|||:|||||..|:|||:|.:
  Rat   355 RLSQQIASHVVSTATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLVILGVVALFTVPLL 419

  Fly   561 YENNKQSIDTHLDLVRSKLTEITDKIRVAIP-IGNKKPEAAAESEKDK 607
            |..::..||.::.||.|:|:.|..|||..|| .|...|.|:....|.|
  Rat   420 YRQHQAQIDQYVGLVTSQLSHIKAKIRAKIPGTGTLAPAASVSGSKAK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtnl1	NP_001162875.1	Reticulon	411..575	CDD:460562	65/163 (40%)
Rtn2	NP_963856.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..180		42/213 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..238		7/36 (19%)
		Reticulon	270..434	CDD:460562	65/163 (40%)