Protein Alignment CG8892 and UBXN7

DIOPT Version :9

• Sequence 1: NP_001260064.1
• Gene: CG8892 / 33719
• FlyBaseID: FBgn0031664
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_056377.1
• Gene: UBXN7 / 26043
• HGNCID: 29119
• Length: 489
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 152/547 - (27%)
• Similarity: 236/547 - (43%)
• Gaps: 139/547 - (25%)

  Fly     2 STTEAPDALVEQVREVTACSMDEAKYYLSACANDVSAAVALFFEQAASTSTPSGSSAGAAAESLP 66
            :.:.|...|::|...:|..|....|:.|.||.|::..||.:|.:.......||.|||..:... |
Human     8 AASSALKGLIQQFTTITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSSASVSTVR-P 71

  Fly    67 VLDDEDEVRAPIAPVREQLILPEDDNFFASGSSSRLSRVTQRVKVHPLRDFAREGALMEEQLQAT 131
              ..|:||||||...:|.|:.||.    ..|:..|  |...|......|||..|....|::|:..
Human    72 --HTEEEVRAPIPQKQEILVEPEP----LFGAPKR--RRPARSIFDGFRDFQTETIRQEQELRNG 128

  Fly   132 GVYADPNRIRRGRAAQMVVAGQAMALNRRSTTDTATSTSRLGDLFRPPTDILYSGSLTAAREFAT 196
            |                       |::::.||        |.||||||.|:::.||...|:|...
Human   129 G-----------------------AIDKKLTT--------LADLFRPPIDLMHKGSFETAKECGQ 162

  Fly   197 KRQRWLLVNVQD-ENFQSQTLNRDVWSDKELKKLIRRQFTFWQVDNDTSEGRRFVAFYHCATLPY 260
            .:.:||::|:|: ::|..|.|||||||::.:|.:||..|.||||.:|:.||:|::.||.....||
Human   163 MQNKWLMINIQNVQDFACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPY 227

  Fly   261 ICVIDPRTGEEV--WRSAEPKLENILPDLRQFLKEHRDFIQEDAPGTSKRSATYIDDDEVPDPEA 323
            :.::|||||:::  |...:  :.:.|..:..||.||.   |.|...:|              |..
Human   228 VSILDPRTGQKLVEWHQLD--VSSFLDQVTGFLGEHG---QLDGLSSS--------------PPK 273

  Fly   324 SCSSTASSKEMPKKRAKVLELTEEEQLELAIKNSINENGGGGGEGNQKNDSPDGASDNES----- 383
            .|:.:.|          :::.:|:.|||.||:.|:.|......:..|     |..||.||
Human   274 KCARSES----------LIDASEDSQLEAAIRASLQETHFDSTQTKQ-----DSRSDEESESELF 323

  Fly   384 --LEEF-------DDEELKGVAAASFENH--LGEAKTE----LTALKLRL--------------- 418
              .|||       ::||::.:|.:....|  ||..|.|    ||...:|.
Human   324 SGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENRRPLTEPPVRTDPGTATNHQGLPAVD 388

  Fly   419 -----------------LNAAGTDEMVQLRWPSDTKLQTLRL----YISQTHKHIPQDGY----- 457
                             ::..|....:.||:| |.|.:.:.|    .:....||:...||
Human   389 SEILEMPPEKADGVVEGIDVNGPKAQLMLRYP-DGKREQITLPEQAKLLALVKHVQSKGYPNERF 452

  Fly   458 KLICAFPRKFLEAEHNDSSLKELGLHP 484
            :|:..|||:.|.....|.:|:|.||.|
Human   453 ELLTNFPRRKLSHLDYDITLQEAGLCP 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8892	NP_001260064.1	UBA_4	9..46	CDD:291236	12/36 (33%)
		UAS	183..294	CDD:239256	42/113 (37%)
		UBQ	412..488	CDD:294102	24/114 (21%)
UBXN7	NP_056377.1	UBA_UBXD7	16..51	CDD:270530	12/34 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..77		7/23 (30%)
		UAS	149..261	CDD:239256	42/113 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..384		21/88 (24%)
		UBX_UBXN7	412..487	CDD:340471	21/69 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8369
eggNOG	1	0.900	-	-		E1_KOG1364
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4122
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1130151at2759
OrthoFinder	1	1.000	-	-		FOG0002610
OrthoInspector	1	1.000	-	-		oto88804
orthoMCL	1	0.900	-	-		OOG6_103779
Panther	1	1.100	-	-	LDO	PTHR23322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5124
SonicParanoid	1	1.000	-	-		X1968
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860