DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gmd and gmds

DIOPT Version :9

Sequence 1:	NP_608888.2	Gene:	Gmd / 33716	FlyBaseID:	FBgn0031661	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001032330.1	Gene:	gmds / 394693	XenbaseID:	XB-GENE-943015	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	362	Identity:	251/362 - (69%)
Similarity:	301/362 - (83%)	Gaps:	1/362 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 NGTEAGAEGDSRDKVALITGITGQDGSYLAEFLLKKDYEVHGIIRRASTFNTTRIEHLYADPKAH 98
            :|:.:...|.|| |||||||||||||||||||||:|.||||||:||:|:|||.||||||.:|.||
Frog     9 SGSPSNGAGKSR-KVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPHAH 72

  Fly    99 KGGRMKLHYGDMTDSSSLVKIINMVKPTEIYNLAAQSHVKVSFDLSEYTAEVDAVGTLRILDAIR 163
            ..|.|||||||:|||:.||||||.|||||||||.||||||:||||:||||:||.:||||:|||.:
Frog    73 IEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGLGTLRLLDATK 137

  Fly   164 TCGMEKNVRFYQASTSELYGKVVETPQNEQTPFYPRSPYACAKMYGFWIVINYREAYNMYACNGI 228
            |||:..:|:|||||||||||||.|.||.|.|||||||||..||:|.:|||:|:|||||::|.|||
Frog   138 TCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGI 202

  Fly   229 LFNHESPRRGENFVTRKITRSVAKIYHKQMEYFELGNLDSKRDWGHASDYVEAMWMMLQRESPSD 293
            |||:||||||.|||||||:||||||:..|||:..|||||:|||||||.|||||||:|||.:.|.|
Frog   203 LFNYESPRRGANFVTRKISRSVAKIHLGQMEFVSLGNLDAKRDWGHAKDYVEAMWLMLQTDEPED 267

  Fly   294 YVIATGETHSVREFVEAAFKHIDREITWKGKGVDEVGVENGTGIVRVRINPKYFRPTEVDLLQGD 358
            :||:|||.||||||||.||.||.:.|.|:||..:|||..:.||.:.|:::.||:|||||:.||||
Frog   268 FVISTGEVHSVREFVEKAFMHIGKTIVWEGKNENEVGRCSETGKIHVKVDHKYYRPTEVEFLQGD 332

  Fly   359 ASKANRELNWTPKVTFVELVSDMMKADIELMRKNPIA 395
            .|||..:|.|.|||:|.|||.:|::||||||:.||.|
Frog   333 CSKAKNKLGWIPKVSFNELVKEMVEADIELMKTNPNA 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gmd	NP_608888.2	NADB_Rossmann	47..389	CDD:304358	242/341 (71%)
Gmd	NP_608888.2	GDP_Man_Dehyd	50..381	CDD:292973	234/330 (71%)
gmds	NP_001032330.1	gmd	21..363	CDD:273644	242/341 (71%)
gmds	NP_001032330.1	GDP_Man_Dehyd	24..355	CDD:292973	234/330 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	492	1.000	Domainoid score	I372
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H75968
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1322
OMA	1	1.010	-	-		QHG61241
OrthoDB	1	1.010	-	-		D305068at33208
OrthoFinder	1	1.000	-	-		FOG0004405
OrthoInspector	1	1.000	-	-		oto104786
Panther	1	1.100	-	-	LDO	PTHR43715
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3125
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080