DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14043 and kifbp

DIOPT Version :9

Sequence 1:	NP_608886.1	Gene:	CG14043 / 33714	FlyBaseID:	FBgn0031659	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_001072796.1	Gene:	kifbp / 780257	XenbaseID:	XB-GENE-5934501	Length:	616	Species:	Xenopus tropicalis

Alignment Length:	608	Identity:	185/608 - (30%)
Similarity:	323/608 - (53%)	Gaps:	32/608 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ELYEKANRLVEEESRNDPPTDPFRSHYKARDVLIVLKKQL---DDQLVSVQASEE--DG------ 66
            |.|.:|..|.:.||:|||..:|:||.|:||::|..::..|   :::....:..||  ||
Frog    10 ETYRRAITLSDVESKNDPENEPYRSKYRARELLREVRVLLCPEEEEESEAEGKEERRDGPESGGR 74

  Fly    67 -GQDDRCYHSLLAFVCRDLGRIYIYTEEQAEGEKMLNRCLELVTPFKECPEGIIPFIGAINELSI 130
             |:......:.||.|...||..:..|||.:.||:.|.:...::..|:...||:..:|.|.|.|.|
Frog    75 RGESGELLAARLAVVEFRLGLNHTETEEMSAGEEHLVKSGRIMERFRLSEEGVSVYIQAQNNLGI 139

  Fly   131 VLASKEEYNKGLEILLEAEKIYEDFKASGLKPLAIQDVFNPPEEGQQSHEAGPKELESLYTLVSF 195
            :.|.:.|.......|..||.:|..:.....||....|.....||.:.:.:...|..|.:||...:
Frog   140 LWADRGEIRVAQRYLESAESLYYQYMKEIGKPAIDPDEHFFSEEQKLTEQERTKRFERVYTHTLY 204

  Fly   196 YMAQMYGHLGEPEKSAKCCHRTLHRQLESKTYDPIDFALNTATLSQFYIGEKRFEEARHHLAAAT 260
            |:||:|.||.:.||:|:.||.||.||||..:|:|:::|:|.|||||:|:.::.:.|:||.||||.
Frog   205 YLAQVYKHLKQDEKAAQYCHTTLQRQLEYDSYNPVEWAINAATLSQYYVTKQCYMESRHCLAAAN 269

  Fly   261 LIMAEYE-VHMLEPEMSEKQRQDVSETFKHRYADVARCWAKYGLYLMNTSKLRLMRDEDDEDAKN 324
            :|.::.| :...|.....:..|:..:..:.:.|::||||.||.|.|:..::.:|   ||:....:
Frog   270 VIFSKAEQIPSAEAAKENEAEQERLDLLRQKKAEIARCWVKYCLNLLQDARKKL---EDNIGELD 331

  Fly   325 LEI-----VLRNMRLVEAEQSR-----FPGLDL----TACENRISCEYCLTFDDAKLVFHFVNEW 375
            ::|     ..|.....|.|:.|     |...|:    .|.|.::.|.:.|.|.:|:.||.....:
Frog   332 VDIQEELKAQRQKEEDEKEKDRKKAILFGSSDIYDSVQAAEEKVECSHPLDFKEAREVFLVGQNY 396

  Fly   376 LDIAKDYYKAENEATEYSKIMQDYAEAYEHIAFFEENPENQAKMQKRRAKYLEDLLDLLDPIFYM 440
            ::.:|:|::.:...|::.:|:||::..::.:|||||:.|.:.||.|||...||.|...|:|.:|:
Frog   397 INESKEYFQLDGHVTDHIEIIQDHSSLFKLLAFFEEDYERRCKMHKRRIDMLEPLCKELNPQYYL 461

  Fly   441 KICRECWYGAGTAHAAVMDVRLDIIRATSTPAPEDIKKVNQSCMKAIKHFESYVKSYLVKPPSEE 505
            .|||:..:........:||:::.|...........|||:|.....|||::|.::.|  ::.|.::
Frog   462 LICRQLQFELADTSYEMMDLKVAIGNKLDEMDTHTIKKINSLAQTAIKYYEMFLDS--LRSPDQK 524

  Fly   506 WRPNMDVEEQRHMLYAHFHIGRIYYKLISGHPLQQLEHLTSCHTYYQRFDAGCQLHKEAAETLQG 570
            :...::.:..|..:.|.|.|.|:|.||||.....|||::......|:.....|:::|||.:.::.
Frog   525 FPEKLEEDVLRPAMVAKFRIARLYGKLISTDGKIQLENIQKSLNNYKYIVDYCEINKEAIKCIET 589

  Fly   571 EIGVVREMLQLLPLKINTIKARL 593
            |:.:.:||:.|||.::..::.:|
Frog   590 ELELSKEMVALLPTRMERLRIQL 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14043	NP_608886.1	KBP_C	230..589	CDD:372033	109/373 (29%)
kifbp	NP_001072796.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	52..78		5/25 (20%)
kifbp	NP_001072796.1	KBP_C	239..608	CDD:372033	109/373 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3461
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9223
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2747
OMA	1	1.010	-	-		QHG55856
OrthoDB	1	1.010	-	-		D1516717at2759
OrthoFinder	1	1.000	-	-		FOG0007963
OrthoInspector	1	1.000	-	-		oto104606
Panther	1	1.100	-	-	LDO	PTHR46321
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5906
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080